Regular ArticleImmune System Alteration in the Rat after Indirect Exposure to Methyl Mercury Chloride or Methyl Mercury Sulfide☆,☆☆
References (43)
- et al.
Complexing and denaturation of DNA by methylmercury hydroxide
J. Mol. Biol.
(1966) - et al.
Methyl mercury exposure via placenta and milk impairs natural killer (NK) cell function in newborn rats
Toxicol. Lett.
(1991) - et al.
Placental transfer of mercuric nitrate and methyl mercury in rats
Am. J. Obstet. Gynecol.
(1974) - et al.
Taxol protects the microtubules of Concanavalin A activated lymphocytes from disassembly by methylmercury, but DNA synthesis is still inhibited
Exp. Cell Res.
(1991) - et al.
Distribution and excretion of mercuric chloride in neonatal rats
Toxicol. Appl. Pharmacol.
(1979) - et al.
Methyl mercury poisoning in Iraq. An interuniversity report
Science
(1973) The effect of a subacute methylmercury coated grain poisoning on the progeny
Soviet. Med.
(1968)- et al.
Developmental changes in the biliary excretion of methyl mercury and glutathione
Science
(1982) - et al.
Interleukin-2 production in brown-Norway rats with HgCl2in vivoin vitro
Clin. Exp. Immunol.
(1988) - et al.
Methylmercury in fish: A toxicologic-epidemiologic evaluation of risks—Report of an expert group
Nord. Hyg. Tidsskr. Suppl.
(1971)
Accumulation and Retention of mercury in the mouse. I. An autoradiographic study after single intravenous injection of mercuric chloride
Arch. Environ. Health
Mercury
Changing Metal Cycles and Human Health
Reproductive and developmental toxicity of metals
Scand. J. Work Environ. Health
Alkyl mercury poisoning
Acta Paediatr. Scand.
Experimental studies on organic mercury poisoning on the behavior of Minamata disease causal agent in the maternal bodies and its transference to their infants via either placenta or breast milk
J. Kumamoto Med. Soc.
From Hippocrates to Ramazzini: Early history of industrial Medicine
Ann. Med. Hist.
In vitro effects of HgCl2+
J. Immunol.
Immunosuppression produced by lead, cadmium, and mercury
Am. J. Vet. Res.
Methylmercury: Effect on oncogenic and nononcogenic viruses in Mice
Am. J. Vet. Res.
Polarization of the Golgi apparatus and the microtubule-organizing center within cloned natural killer cells bound to their targets
Proc. Natl. Acad. Sci. USA
Role of tubulin -SH groups in polymerization to microtubules
J. Biochem.
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2024, Journal of Trace Elements in Medicine and BiologyMethylmercury chloride exposure exacerbates existing neurobehavioral and immune dysfunctions in the BTBR T<sup>+</sup> Itpr3<sup>tf</sup>/J mouse model of autism
2022, Immunology LettersCitation Excerpt :Extensive evidence suggests that children with ASD represent a population vulnerable to the adverse effects of mercury [35]. These previous studies have used a variety of tissues, including brain tissues and blood samples [58, 62], and investigated the effects of MeHgCl exposure demonstrating an altered immune system [64]. Several previous studies have also reported the efficacy of MeHgCl in inducing neurotoxic effects when exposed to experimental animals [1, 56].
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2017, Reproductive and Developmental ToxicologyDietary selenium protect against redox-mediated immune suppression induced by methylmercury exposure
2014, Food and Chemical ToxicologyCitation Excerpt :As shown in Fig. 2, the inhibition effects of MeHg on B cells (LPS as mitogen) was more significant than on T cells (ConA as mitogen), which was in accordance with the higher LD50 for MeHg in T cells as compared with B cells (Shenker et al., 1992), indicating the higher sensitivity of B cells to MeHg-induced toxicity. It should be noticed that, in genetically susceptible mice, the immunosuppression effect induced by MeHg could be superseded by autoimmunity with autoantibody production (Vas and Monestier, 2008), such process might be help in explaining the stimulation of lymphoproliferation after MeHg exposure (for 6 weeks or longer) in some studies (Thuvander et al., 1996; Wild et al., 1997). Methylmercury has been reported to generate ROS formation, such as superoxide anion, hydrogen peroxide, and hydroxyl radicals (Ali et al., 1992).
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2011, Reproductive and Developmental Toxicology
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The animal studies were approved by the Institutional Advisory Committee for Animal Resources at Tulane University Medical School. This guarantees treatment under the recommendations of the American Veterinary Medical Association.
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J. O. Nriagu, Ed.