ArticlesProlonged Controlled-Release of Nafarelin, a Luteinizing Hormone-Releasing Hormone Analogue, from Biodegradable Polymeric Implants: Influence of Composition and Molecular Weight of Polymer
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2010, BiomaterialsCitation Excerpt :The most investigated method is an encapsulation of hGH to poly(lactic acid-co-glycolic acid) (PLGA) microsphere. PLGA is a biodegradable polymer and approved in market for sustained release formulation of peptides such as luteinizing hormone-releasing hormone (LHRH) analogues [11,12]. However, developing sustained release formulation of proteins including hGH has been hampered due to their complex structure which is related to protein activity.
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