Preliminary Communications
Trimethoprim and Sulphamethoxazole in Typhoid
Br Med J 1968; 3 doi: https://doi.org/10.1136/bmj.3.5620.721 (Published 21 September 1968) Cite this as: Br Med J 1968;3:721
- O. O. Akinkugbe,
- E. A. Lewis,
- D. Montefiore,
- O. A. Okubadejo
Abstract
Six patients with proved typhoid fever were treated with a combination of trimethoprim and sulphamethoxazole; four others were treated with chloramphenicol. All ten patients made an uneventful recovery.
Though the numbers are small it appears that the patients treated with the combined drugs did just as well as those treated with chloramphenicol, and fever seemed to subside quicker with the combined drugs.
Trimethoprim and sulphamethoxazole have low toxicities, so further studies of their use in the treatment of typhoid are justified.
Log in
Log in using your username and password
Log in through your institution
Subscribe from £173 *
Subscribe and get access to all BMJ articles, and much more.
* For online subscription
Access this article for 1 day for:
£38 / $45 / €42 (excludes VAT)
You can download a PDF version for your personal record.