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Distribution and ultrastructure of tyrosine hydroxylase-positive neurons in CNS of bivalve mollusc Megangulus venulosus under action of elevated temperature and hypoxia

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Abstract

Using the immunocytochemical methods of light microscopy and electron microscopy, the distribution and ultrastructure of tyrosine hydroxylase (TH)-positive neurons was studied in the CNS of the bivalve mollusc Megangulus venulosus in norm and under the complex action of elevated temperature and hypoxia. The simultaneous effect of elevated temperature and hypoxia has been established to produce changes in the number and structure of TH-immunopositive neurons. The most significant changes in the CNS of M. venulosus were revealed after 60-min action and included the selective damage of processes of large neurons, the destruction of some synapses, and a decrease in TH-immunoreactivity in neurons and neuropil.

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Abbreviations

DA:

dopamine

CA:

catecholamines

NA:

noradrenaline

TH:

tyrosine hydroxylase

L-DOPA:

L-dihydroxyphenylalanin

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Authors and Affiliations

  1. Zhirmunsky Institute of Marine Biology, Far East Branch, Russian Academy of Sciences, Vladivostok, Russia

    E. P. Kotsyuba

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  1. E. P. Kotsyuba
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Correspondence to E. P. Kotsyuba.

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Original Russian Text © E.P. Kotsyuba, 2011, published in Tsitologiya, Vol. 53, No. 6, 2011, pp. 498–504.

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Kotsyuba, E.P. Distribution and ultrastructure of tyrosine hydroxylase-positive neurons in CNS of bivalve mollusc Megangulus venulosus under action of elevated temperature and hypoxia. Cell Tiss. Biol. 5, 264–272 (2011). https://doi.org/10.1134/S1990519X11030047

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