Endoscopy 2014; 46(08): 650-655
DOI: 10.1055/s-0034-1365721
Original article
© Georg Thieme Verlag KG Stuttgart · New York

Utility of endoscopic ultrasound to diagnose remnant stones in symptomatic patients after cholecystectomy

Mehdi Mohamadnejad
1   Digestive Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran
2   Gastrointestinal and Liver Disease Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Sayed Jalal Hashemi
3   Department of Medicine, Division of Gastroenterology, Ahvaz University of Medical Sciences, Ahvaz, Iran
,
Farhad Zamani
2   Gastrointestinal and Liver Disease Research Center, Iran University of Medical Sciences, Tehran, Iran
,
Massoud Baghai-Wadji
4   Department of Surgery, Firouzgar Hospital, Iran University of Medical Sciences, Tehran, Iran
,
Reza Malekzadeh
1   Digestive Disease Research Center, Tehran University of Medical Sciences, Tehran, Iran
,
Mohamad A. Eloubeidi
5   Department of Medicine, Division of Gastroenterology, American University of Beirut, Beirut, Lebanon
› Author Affiliations
Further Information

Publication History

submitted 01 April 2013

accepted after revision 24 March 2014

Publication Date:
30 June 2014 (online)

Background and study aims: Stones in the cystic duct stump (CDS) or gallbladder remnant after cholecystectomy are difficult to identify. The aim of this study was to evaluate the utility of endoscopic ultrasound (EUS) in the diagnosis of stones in the CDS or gallbladder remnant in patients with postcholecystectomy syndrome.

Methods: A prospective study was conducted between January 2011 and December 2012 in consecutive patients with pancreaticobiliary-type pain or acute pancreatitis (n = 112) following cholecystectomy. Diagnostic modalities including EUS were used to diagnose the cause of postcholecystectomy syndrome.

Results: A total of 11 patients (10 %) were found to have stones in the gallbladder remnant (n = 8), CDS (n = 2), or both (n = 1). In eight patients, EUS was the first imaging procedure to make the diagnosis. Seven patients agreed to undergo repeat surgery, and six of them remained free of symptoms postoperatively after a median follow-up period of 4 months (range 1 – 13 months).

Conclusion: EUS may be an important procedure to consider in the study of patients with symptoms after cholecystectomy, as the diagnosis of residual stones is frequently missed by other imaging modalities.

 
  • References

  • 1 Girometti R, Brondani G, Cereser L et al. Post-cholecystectomy syndrome: spectrum of biliary findings at magnetic resonance cholangiopancreatography. Br J Radiol 2010; 83: 351-361
  • 2 McHardy C. Postcholecystectomy syndrome. Dis Mon 1959; 1: 1-40
  • 3 Anand AC, Sharma R, Kapur BM et al. Analysis of symptomatic patients after cholecystectomy: is the term post-cholecystectomy syndrome an anachronism?. Trop Gastroenterol 1995; 16: 126-131
  • 4 Russello D, Di Stefano A, Scala R et al. Does cholecystectomy always resolve biliary disease?. Minerva Chir 1997; 52: 1435-1439
  • 5 Bates T, Ebbs SR, Harrison M et al. Influence of cholecystectomy on symptoms. Br J Surg 1991; 78: 964-967
  • 6 Hogan W. The post-cholecystectomy syndrome: the role of sphincter-of-Oddi dysfunction. Bildgebung 1992; 59: 42-50
  • 7 Walsh RM, Ponsky JL, Dumot J. Retained gallbladder/cystic duct remnant calculi as a cause of postcholecystectomy pain. Surg Endosc 2002; 16: 981-984
  • 8 Flörcken H. Gallenblasenregeneration mit Steinrecidiv nach Cholecystectomie. Deutsch Z Chir 1912; 113: 604
  • 9 Samuel E. The radiological anatomy of the biliary passages with especial reference to the post-cholecystectomy syndrome. Ann R Coll Surg Engl 1957; 20: 157-176
  • 10 Glenn F, Johnson Jr G. Cystic duct remnant, a sequela of incomplete cholecystectomy. Surg Gynecol Obstet 1955; 101: 331-345
  • 11 Bodvall B, Overgaard B. Cystic duct remnant after cholecystectomy: incidence studied by cholegraphy in 500 cases, and significance in 103 reoperations. Ann Surg 1966; 163: 382-390
  • 12 Rogy MA, Függer R, Herbst F et al. Reoperation after cholecystectomy. The role of the cystic duct stump. HPB Surg 1991; 4: 129-134
  • 13 Laing FC, Jeffrey Jr RB. Choledocholithiasis and cystic duct obstruction: difficult ultrasonographic diagnosis. Radiology 1983; 146: 475-479
  • 14 Macaron C, Qadeer MA, Vargo JJ. Recurrent abdominal pain after laparoscopic cholecystectomy. Cleve Clin J Med 2011; 78: 171-178
  • 15 Hassan H, Vilmann P. Insufficient cholecystectomy diagnosed by endoscopic ultrasonography. Endoscopy 2004; 36: 236-238
  • 16 Dewitt JM, Levy MJ, Fockens P. Learning EUS tricks from the masters. Gastrointest Endosc 2011; 74: 1116-1118
  • 17 Catalano MF, Sahai A, Levy M et al. EUS-based criteria for the diagnosis of chronic pancreatitis: the Rosemont classification. Gastrointest Endosc 2009; 69: 1251-1261
  • 18 Sharma SS. Sphincter of Oddi dysfunction in patients addicted to opium: an unrecognized entity. Gastrointest Endosc 2002; 55: 427-430
  • 19 Mousavi S, Toussy J, Zahmatkesh M. Opium addiction as a new risk factor of sphincter of Oddi dysfunction. Med Sci Monit 2007; 13: CR528-531
  • 20 Puente SG, Bannura GC. Radiological anatomy of the biliary tract: variations and congenital abnormalities. World J Surg 1983; 7: 271-276
  • 21 Walsh RM, Chung RS, Grundfest-Broniatowski S. Incomplete excision of the gallbladder during laparoscopic cholecystectomy. Surg Endosc 1995; 9: 67-70
  • 22 Katsohis C, Prousalidis J, Tzardinoglou E et al. Subtotal cholecystectomy. HPB Surg 1996; 9: 133-136
  • 23 Maingot R. Complications of cholecystectomy. Lecture delivered at the Royal College of Surgeons of England on 25th September 1962. Ann R Coll Surg Engl 1963; 32: 42-58
  • 24 Shamiyeh A, Danis J, Wayand W et al. A 14-year analysis of laparoscopic cholecystectomy: conversion – when and why?. Surg Laparosc Endosc Percutan Tech 2007; 17: 271-276
  • 25 Kaafarani HM, Smith TS, Neumayer L et al. Trends, outcomes, and predictors of open and conversion to open cholecystectomy in Veterans Health Administration hospitals. Am J Surg 2010; 200: 32-40
  • 26 Calvo MM, Bujanda L, Heras I et al. Magnetic resonance cholangiography versus ultrasound in the evaluation of the gallbladder. J Clin Gastroenterol 2002; 34: 233-236
  • 27 Shami VM, Talreja JP, Mahajan A et al. EUS-guided drainage of bilomas: a new alternative?. Gastrointest Endosc 2008; 67: 136-140