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Effect of dobutamine stress on basal septal tissue dynamics in hypertensive patients with basal septal hypertrophy

Journal of Human Hypertension volume 20, pages 628–630 (2006)Cite this article

Left ventricular outflow tract (LVOT) obstruction has been classically observed in hypertrophic cardiomyopathy in which the LVOT obstruction is associated with asymmetric septal hypertrophy producing a systolic pressure gradient across the LVOT.1 Basal septal hypertrophy (BSH) with hypertension may result in dynamic LVOT obstruction as well.2, 3 It was suggested that regional hypertrophy may be related to enhanced ventricular dynamics.4

We have previously observed a significant correlation between decreased LVOT area and LVOT gradients in patients with hypertrophic cardiomyopathy using real-time three dimensional echocardiography.5 In hypertrophic cardiomyopathy, left ventricular (LV) wall thickening is associated with a nondilated and hyperdynamic chamber (often with systolic cavity obliteration) in the absence of another cardiac or systemic disease (e.g., hypertension or aortic stenosis) capable of producing the magnitude of hypertrophy evident, and independent of whether or not LVOT obstruction is present.1

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References

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Acknowledgements

This study has been an oral presentation in the 19th European Congress of International Society of Noninvasive Cardiology, Istanbul, 2003.

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Authors and Affiliations

  1. Department of Cardiology, Mustafa Kemal University School of Medicine, Hatay, Turkey

    F Yalçin

  2. Department of Cardiology, Başkent University School of Medicine, Ankara, Turkey

    F Yiǧit, T Erol, M Baltali, M E Korkmaz & H Müderrisoǧlu

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  1. F Yalçin
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  2. F Yiǧit
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  3. T Erol
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  4. M Baltali
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  6. H Müderrisoǧlu
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Correspondence to F Yalçin.

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Yalçin, F., Yiǧit, F., Erol, T. et al. Effect of dobutamine stress on basal septal tissue dynamics in hypertensive patients with basal septal hypertrophy. J Hum Hypertens 20, 628–630 (2006). https://doi.org/10.1038/sj.jhh.1002041

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