Proliferating cells of the Xenopus laevis retina facultatively use aerobic glycolysis instead of oxidative phosphorylation. This demonstrates that the metabolic rewiring usually associated with the Warburg effect in tumorigenesis may be a more widespread feature of proliferative metabolism than generally appreciated.
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Fiske, B., Vander Heiden, M. Seeing the Warburg effect in the developing retina. Nat Cell Biol 14, 790–791 (2012). https://doi.org/10.1038/ncb2554
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DOI: https://doi.org/10.1038/ncb2554
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