Cell Host & Microbe
Volume 17, Issue 4, 8 April 2015, Pages 423-425
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The Multidimensional Nature of Antiviral Innate Immunity

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Viruses possess elaborate defensive mechanisms to evade host innate immune responses. In this issue of Cell Host & Microbe, Stavrou et al. (2015) reveal how the murine leukemia virus uses a sugar-protein shield to protect from inevitable destruction by cellular innate immune factors including the APOBEC3 DNA mutating enzyme.

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