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Prevalence and characteristics of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae isolated from rural well water in Taian, China, 2014

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Abstract

The production of extended-spectrum beta-lactamase (ESBL) is one of the major antimicrobial resistance mechanisms in Enterobacteriaceae, and the increasing number of ESBL-producing Enterobacteriaceae isolated from water environments has posed a serious threat to the public health. The study aimed to analyze prevalence and characterization of ESBL-producing Enterobacteriaceae from rural well waters in Taian, China. A total of 10 isolates expressing an ESBL phenotype, including 9 Escherichia coli (E. coli) and 1 Klebsiella pneumoniae (K. pneumoniae) was obtained from 4 (4 %) out of the 100 sampled wells. ESBL genotype revealed that 9 expressed CTX-M-15 and 1 produced CTX-M-27. Five out of 8 ESBL-producing E. coli expressing CTX-M-15 belonged to ST10, which are mostly detected from human feces in China. Importantly, the only strain of CTX-M-27-producing E. coli belonged to multi-locus sequence type B2:131 (ST131), which may be related with severe infection in humans and animals.

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Authors and Affiliations

  1. College of Animal Science and Technology, Shandong Agricultural University, Daizong Street 61, Taian, 271000, China

    Hongna Zhang, Shuyuan Guo & Weishan Chang

  2. College of Animal Science and Technology, Shanxi Agricultural University, Taigu, 030800, China

    Yufa Zhou

  3. Disease Controlling Center, Veterinary Bureau of Daiyue Region, Taian, 271000, China

    Yufa Zhou

Authors
  1. Hongna Zhang
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  2. Yufa Zhou
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  3. Shuyuan Guo
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  4. Weishan Chang
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Correspondence to Hongna Zhang or Weishan Chang.

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Responsible editor: Robert Duran

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Zhang, H., Zhou, Y., Guo, S. et al. Prevalence and characteristics of extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae isolated from rural well water in Taian, China, 2014. Environ Sci Pollut Res 22, 11488–11492 (2015). https://doi.org/10.1007/s11356-015-4387-9

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  • DOI: https://doi.org/10.1007/s11356-015-4387-9

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