ABSTRACT
There is a tremendous amount of literature regarding the pathology of colon
carcinoma associated with Lynch syndrome. Unfortunately, there is much less
information available for Lynch syndrome-associated endometrial cancer and
even less for Lynch syndrome-associated ovarian cancer. The bulk of this
chapter will therefore focus on what is known regarding endometrial cancer in
Lynch syndrome. Some attention will be devoted to ovarian cancer as well.
Finally, a tissue-based approach to identifying endometrial and ovarian cancer
patients with Lynch syndrome will be discussed.