ABSTRACT

There is a tremendous amount of literature regarding the pathology of colon

carcinoma associated with Lynch syndrome. Unfortunately, there is much less

information available for Lynch syndrome-associated endometrial cancer and

even less for Lynch syndrome-associated ovarian cancer. The bulk of this

chapter will therefore focus on what is known regarding endometrial cancer in

Lynch syndrome. Some attention will be devoted to ovarian cancer as well.

Finally, a tissue-based approach to identifying endometrial and ovarian cancer

patients with Lynch syndrome will be discussed.