The Journal of Antibiotics
Online ISSN : 1881-1469
Print ISSN : 0021-8820
ISSN-L : 0021-8820
VICENISTATIN, A NOVEL 20-MEMBERED MACROCYCLIC LACTAM ANTITUMOR ANTIBIOTIC
KAZUTOSHI SHINDOMASARU KAMISHOHARAATSUO ODAGAWAMICHIKO MATSUOKAHIROYUKI KAWAI
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1993 Volume 46 Issue 7 Pages 1076-1081

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Abstract

A new antitumor antibiotic vicenistatin was isolated from the culture broth of Streptomyces sp. HC34. The structure of vicenistatin was elucidated by NMR spectral analysis. Vicenistatin exhibited antitumor activity against human colon carcinoma Co-3 in the xenograft model.

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© Japan Antibiotics Research Association
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