New Antibiotics Phthoxazolins B, C and D Produced by Streptomyces sp. KO-7888

KAZURO SHIOMI; NORIKO ARAI; MAYUMI SHINOSE; YOKO TAKAHASHI; HLROSHI YOSHIDA; JUN IWABUCHI; YOSHITAKE TANAKA; SATOSHI OMURA

doi:10.7164/antibiotics.48.714

New Antibiotics Phthoxazolins B, C and D Produced by Streptomyces sp. KO-7888

KAZURO SHIOMI, NORIKO ARAI, MAYUMI SHINOSE, YOKO TAKAHASHI, HLROSHI YOSHIDA, JUN IWABUCHI, YOSHITAKE TANAKA, SATOSHI OMURA

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JOURNAL FREE ACCESS

1995 Volume 48 Issue 7 Pages 714-719

DOI https://doi.org/10.7164/antibiotics.48.714

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Abstract

New antibiotics, phthoxazolins B, C and D were isolated from the fermentation broth of Streptomyces sp. KO-7888. They are geometrical isomers of 10-hydroxyphthoxazolin A. They showed selective antifungal activity against Phytophthora parasitica in vitro and modest herbicidal activity in a laboratory test, but the potencies were different among isomers.

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