THIOTETROMYCIN, A NEW ANTIBIOTIC TAXONOMY, PRODUCTION, ISOLATION, AND PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES

SATOSHI OMURA; YUZURU IWAI; AKIRA NAKAGAWA; RIMIKO IWATA; YOKO TAKAHASHI; HIDEKI SHIMIZU; HARUO TANAKA

doi:10.7164/antibiotics.36.109

SATOSHI OMURA, YUZURU IWAI, AKIRA NAKAGAWA, RIMIKO IWATA, YOKO TAKAHASHI, HIDEKI SHIMIZU, HARUO TANAKA

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JOURNAL FREE ACCESS

1983 Volume 36 Issue 2 Pages 109-114

DOI https://doi.org/10.7164/antibiotics.36.109

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Abstract

A new antibiotic, thiotetromycin, has been isolated from the culture filtrate of Streptomyces sp. OM-674 by solvent extraction and silica gel chromatography. The molecular formula of the antibiotic has been determined as C₁₃H₁₈O₂S on the basis of elemental analysis and its high resolution mass spectrometry. The antibiotic contains a thiotetronic acid in the molecule and possesses a selective activity against Bacteroides fragilis.

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