As the highest institution for academic research in Taiwan, in addition to cultivating advanced academic research talents, Academia Sinica also takes the national long-term basic academic development into consideration, converts the research energy into the motive power of social progress, and plays the role of policy advisor, so as to provide professional suggestions for the State. Taking Academia Sinica as an example, this study explored the effects of knowledge sharing and individual creativity on job performance. In this study, questionnaire survey method and regression analysis were used for empirical analysis. The empirical results show that knowledge sharing and individual creativity have significantly positive effects, meaning both individual creativity and knowledge sharing have the significantly positive effects on job performance. Hence, as the highest institution for academic research in Taiwan, Academia Sinica always uses information technology or systems as the main motivation factor to drive knowledge management or share activities. However, the activity of “knowledge sharing behaviors of organization members” should be greatly valued and implemented at this stage.