With the rapid development of the Internet of Things and the awareness of the global energy crisis, the development of alternative energy sources has become a trend today, and maintaining the power supply requirements of many devices and devices has become a major problem. This paper proposes a power generation system that uses two methods of solar panel power generation combined with temperature difference power generation for energy harvesting. It is hoped that it can be applied to small power products and emergency power in the future. In this paper, the ECL-W0422 boost converter is used to verify the feasibility of power generation after the temperature of the human body is cooled by the human body temperature. However, because the ECL-W0422 is expensive and the development data is opaque, the boost converter is at the price. And development is not competitive. Therefore, this thesis uses the boost IC-LTC3108 for boost converter design. The results show that the LED can be brightened through the body temperature through the cooling chip. In order to avoid the power generation due to the low temperature difference, the solar panel can be combined. The power generation system has two sets of input modes to make the application mode multi-faceted application, which can save 80% cost and increase the competitiveness of the product than the ECL-W0422.