Amyloidosis is a rare systemic disorder caused by extracellular deposition of insoluble fibrils in a wide spectrum of tissues and organs. Among the variety of affected organs, cardiac involvement contributes to the majority of death. Echocardiography and technetium-99m pyrophosphate ((superscript 99m)Tc-PYP) scintigraphy are the common non-invasive imaging modalities in the evaluation of cardiac amyloidosis. In this case report, we present a 65-year-old man with symptoms and signs of congestive heart failure. Cardiac amyloidosis was suspected from his family history. Echocardiography revealed diffuse myocardial hypertrophy and hyperechoic granular sparkling texture in the myocardium. (superscript 99m)Tc-PYP scintigraphy showed diffuse and intense (superscript 99m)Tc-PYP uptake in bilateral ventricular myocardium. The pathological result from a biopsy of subcutaneous fat from the chest wall later confirmed the diagnosis.