Background and Objectives: This study aimed to explore the effect of functional foods on aphasia related to a previous ischemic stroke. When stroke-related neurological deficits result in physical dependency and poor selfcare that persists longer than 6 months, full recovery is almost impossible and the patient often requires long-term care. The functional foods, EASE123 and BioBalance#6, include numerous plant and marine-based nutrient supplements that could prove beneficial for such patients. Methods and Study Design: This open-labelled study included 10 patients diagnosed with prior ischemic stroke and aphasia lasting longer than 6 months. Each patient was administered 6 tablets of EASE123 at 10:30 AM and at 90 minutes before sleeping, and 3 tablets of BioBalance# 6 at 2:30 PM. After a treatment period of 12 weeks, the patients were followed during a 4-week withdrawal period. Functional improvement was assessed by scores and subscores on the Concise Chinese Aphasia Test (CCAT) at weeks 4, 8, 12, and 16. Results: Average total CCAT scores and matching ability improved significantly at weeks 4, 8, 12, and 16 (p＜0.05). Simple response scores improved significantly at weeks 8 and 12 (p＜0.05). Auditory comprehension improved significantly at weeks 4 and 12 (p＜0.05), and reading comprehension, at week 12 (p＜0.05). Repetition ability improved significantly at weeks 8, 12, and 16 (p＜0.05), and spontaneous writing, at weeks 4, 12, and 16 (p＜0.05). Conclusions: Matching, repetition, and average total CCAT scores improved over the course of the study. Therefore, 6 months after ischemic stroke, EASE123 and BioBalance# 6 administration may improve stroke-related aphasia.