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CC BY-NC 4.0 · Arch Plast Surg 2016; 43(03): 284-287
DOI: 10.5999/aps.2016.43.3.284
Case Report

A Rare Case of Pulmonary Epithelioid Hemangioendothelioma Presenting with Skin Metastasis

Hyung-Suk Ro
Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea
,
Jin Yong Shin
Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea
,
Si-Gyun Roh
Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea
,
Nae-Ho Lee
Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea
,
Kyung-Moo Yang
Department of Plastic and Reconstructive Surgery, Chonbuk National University Medical School, Jeonju, Korea
,
Woo-Sung Moon
Department of Pathology, Chonbuk National University Medical School, Jeonju, Korea
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Epithelioid hemangioendothelioma (EHE) is a well-differentiated and rare vascular tumor. Systemic metastases are uncommon. Herein, we present a patient with skin metastasis of pulmonary EHE (PEH) that was treated by wide excision. A 76-year-old male was evaluated due to pulmonary thromboembolism and a solitary pulmonary nodule. A biopsy was performed and pathological examination of the mass confirmed EHE. No metastasis was observed. The patient returned to care approximately two years later due to a painful nodule in the right lower leg. A skin biopsy showed metastatic EHE from the lung. We used a safety margin of 1 cm based on clinical experience, because no prior case had been reported regarding the resection margin appropriate for primary cutaneous EHE and skin metastases of PEH. At four months after surgery, the patient recovered without complications or recurrence. Skin metastasis of PEH is extremely rare, and only two cases have been reported in the literature. In this case, we report a rare case of PEH with histologically diagnosed skin metastasis that was successfully treated by curative resection. It is expected that this case report will provide a helpful contribution to the extant data regarding PEH metastases.

Keywords

Hemangioendothelioma, epithelioid - Skin - Cutaneous surgery


Publication History

Received: 21 December 2015

Accepted: 29 March 2016

Article published online:
20 April 2022

© 2016. The Korean Society of Plastic and Reconstructive Surgeons. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonCommercial License, permitting unrestricted noncommercial use, distribution, and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes. (https://creativecommons.org/licenses/by-nc/4.0/)

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  • References

  • 1 Sardaro A, Bardoscia L, Petruzzelli MF. et al. Pulmonary epithelioid hemangioendothelioma presenting with vertebral metastases: a case report. J Med Case Rep 2014; 8: 201
    CrossrefPubMedGoogle Scholar
  • 2 Sardaro A, Bardoscia L, Petruzzelli MF. et al. Epithelioid hemangioendothelioma: an overview and update on a rare vascular tumor. Oncol Rev 2014; 8: 259
    PubMedGoogle Scholar
  • 3 Yanagawa H, Hashimoto Y, Bando H. et al. Intravascular bronchioloalveolar tumor with skin metastases. Chest 1994; 105: 1882-1884
    CrossrefPubMedGoogle Scholar
  • 4 Requena L, Kutzner H. Hemangioendothelioma. Semin Diagn Pathol 2013; 30: 29-44
    CrossrefPubMedGoogle Scholar
  • 5 Carranza-Romero C, Molina-Ruiz AM, Perna Monroy C. et al. Cutaneous epithelioid hemangioendothelioma on the sole of a child. Pediatr Dermatol 2015; 32: e64-e69
    CrossrefPubMedGoogle Scholar