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99mTc(V)-DMSA SPECT-CT findings in a case of Gorham-Stout disease
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Abstract
The Gorham-Stout disease is a very rare condition, characterized by lymphovascular proliferation and massive bone resorption. We present a 48-year-old male patient with osteolysis involving the left femoral head and neck, as well as to the ipsilateral acetabulum. Besides the morphological imaging, he underwent bone scintigraphy, technetium-99m-V-dimercaptosuccinic acid [99mTc(V)-DMSA] single photon emission computed tomography/computed tomography (SPECT/CT) and histological examination. Together these findings gave the definitive diagnosis. This is the first case ever published with 99mTc(V)-DMSA SPECT-CT. Advances on the knowledge of disease suggests that this imaging procedure could have utility in diagnosis and evaluation of the disease activity and therapy response.
Abstract
The Gorham-Stout disease is a very rare condition, characterized by lymphovascular proliferation and massive bone resorption. We present a 48-year-old male patient with osteolysis involving the left femoral head and neck, as well as to the ipsilateral acetabulum. Besides the morphological imaging, he underwent bone scintigraphy, technetium-99m-V-dimercaptosuccinic acid [99mTc(V)-DMSA] single photon emission computed tomography/computed tomography (SPECT/CT) and histological examination. Together these findings gave the definitive diagnosis. This is the first case ever published with 99mTc(V)-DMSA SPECT-CT. Advances on the knowledge of disease suggests that this imaging procedure could have utility in diagnosis and evaluation of the disease activity and therapy response.
Keywords
99mTc(V)-dimercaptosuccinic acid, bone scintigraphy, Gorham-Stout disease, single-photon emission computed tomography/computed tomography
About this articleTitle
99mTc(V)-DMSA SPECT-CT findings in a case of Gorham-Stout disease
Journal
Issue
Article type
Case report
Pages
97-101
Published online
2015-07-31
Page views
1452
Article views/downloads
2983
DOI
10.5603/NMR.2015.0023
Pubmed
Bibliographic record
Nucl. Med. Rev 2015;18(2):97-101.
Keywords
99mTc(V)-dimercaptosuccinic acid
bone scintigraphy
Gorham-Stout disease
single-photon emission computed tomography/computed tomography
Authors
Victor M. Alves
Tiago S. Vieira
Nelson S. Amorim
Ana Oliveira
André Rodrigues
Jorge G. Pereira
