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Review

Current Treatment Strategies in Malignant Pleural Mesothelioma with a Treatment Algorithm

by
Mutlay Sayan
1,*,
Mehmet Fuat Eren
2,
Apar Gupta
1,
Nisha Ohri
1,
Ayse Kotek
3,
Ibrahim Babalioglu
4,
Sedenay Oskeroglu Kaplan
5,
Ozge Duran
5,
Ozlem Derinalp Or
6,
Funda Cukurcayir
7,
Neslihan Kurtul
8,
Beyhan Ceylaner Bicakci
9,
Tugce Kutuk
10,
Sukran Senyurek
11,
Ali Turk
11,
Salma K. Jabbour
1 and
Banu Atalar
12
1
Rutgers Cancer Institute of New Jersey, New Brunswick, NJ, USA
2
Radiation Oncology Clinic, Marmara University Istanbul Pendik Education and Research Hospital, Istanbul, Turkey
3
Department of Radiation Oncology, Dr. Ersin Arslan Education and Research Hospital, Gaziantep, Turkey
4
Department of Radiation Oncology, Konya Education and Research Hospital, Konya, Turkey
5
Department of Radiation Oncology, Mehmet Akif Inan Education and Research Hospital, Sanliurfa, Turkey
6
Department of Radiation Oncology, Adana City Education and Research Hospital, Adana, Turkey
7
Department of Radiation Oncology, Balikesir Government Hospital, Balikesir, Turkey
8
Department of Radiation Oncology, Kahramanmaras Sutcu Imam University, Kahramanmaras, Turkey
9
Department of Radiation Oncology, Saglik Bilimleri University, Kartal Dr. Lutfi Kirdar Education and Research Hospital, Istanbul, Turkey
10
Department of Radiation Oncology, Malatya Education and Research Hospital, Malatya, Turkey
11
Department of Radiation Oncology, Kahramanmaras Necip Fazil City Hospital, Kahramanmaras, Turkey
12
Department of Radiation Oncology, Mehmet Ali Aydınlar Acıbadem University, School of Medicine, Istanbul, Turkey
*
Author to whom correspondence should be addressed.
Adv. Respir. Med. 2019, 87(5), 289-297; https://doi.org/10.5603/ARM.2019.0051
Submission received: 27 May 2019 / Revised: 3 July 2019 / Accepted: 3 July 2019 / Published: 31 October 2019

Abstract

Malignant pleural mesothelioma (MPM) is arare disease with apoor prognosis. The main therapeutic options for MPM include surgery, chemotherapy, and radiation therapy (RT). Although multimodality therapy has been reported to improve survival, not every medically operable patient is able to undergo all recommended therapy. With improvements in surgical techniques and systemic therapies, as well as advancements in RT, there has been apotential new paradigm in the management of this disease. In this review, we discuss the current literature on MPM management and propose afunctional treatment algorithm.
Keywords: mesothelioma; surgery; chemotherapy; radiotherapy mesothelioma; surgery; chemotherapy; radiotherapy

Share and Cite

MDPI and ACS Style

Sayan, M.; Eren, M.F.; Gupta, A.; Ohri, N.; Kotek, A.; Babalioglu, I.; Kaplan, S.O.; Duran, O.; Derinalp Or, O.; Cukurcayir, F.; et al. Current Treatment Strategies in Malignant Pleural Mesothelioma with a Treatment Algorithm. Adv. Respir. Med. 2019, 87, 289-297. https://doi.org/10.5603/ARM.2019.0051

AMA Style

Sayan M, Eren MF, Gupta A, Ohri N, Kotek A, Babalioglu I, Kaplan SO, Duran O, Derinalp Or O, Cukurcayir F, et al. Current Treatment Strategies in Malignant Pleural Mesothelioma with a Treatment Algorithm. Advances in Respiratory Medicine. 2019; 87(5):289-297. https://doi.org/10.5603/ARM.2019.0051

Chicago/Turabian Style

Sayan, Mutlay, Mehmet Fuat Eren, Apar Gupta, Nisha Ohri, Ayse Kotek, Ibrahim Babalioglu, Sedenay Oskeroglu Kaplan, Ozge Duran, Ozlem Derinalp Or, Funda Cukurcayir, and et al. 2019. "Current Treatment Strategies in Malignant Pleural Mesothelioma with a Treatment Algorithm" Advances in Respiratory Medicine 87, no. 5: 289-297. https://doi.org/10.5603/ARM.2019.0051

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