Genomic data from an extinct Palaeo-Eskimo.

Available here is the genome of a male individual from an extinct Palaeo-Eskimo culture, the first known group of Homo sapiens to settle in Greenland. The DNA sample was obtained from ~4,000-year-old permafrost-preserved hair, and was shown to have very low modern DNA contamination. The diploid genome was sequenced to an average depth of 20x using Illumina GAII sequencing platforms, with 79% recovery. Correct indexed reads were mapped to the human genome (hg18) with a suffix array-based method that allows for residual primer trimming. Sequencing yielded a total of 3.5 billion reads.

Read the peer-reviewed publication(s):

• Rasmussen, M., Li, Y., Lindgreen, S., Pedersen, J. S., Albrechtsen, A., Moltke, I., Metspalu, M., Metspalu, E., Kivisild, T., Gupta, R., Bertalan, M., Nielsen, K., Gilbert, M. T. P., Wang, Y., Raghavan, M., Campos, P. F., Kamp, H. M., Wilson, A. S., Gledhill, A., … Willerslev, E. (2010). Ancient human genome sequence of an extinct Palaeo-Eskimo. Nature, 463(7282), 757–762. https://doi.org/10.1038/nature08835 (PubMed:20148029)

Accessions (data included in GigaDB):

SRA: SRP001453
BioProject: PRJNA46213