Abstract
In this study, we prepared alcohol extracts of the larva, pupa, queen, and cocoon (clony) of B. ignitus, B. ter-restris, and B. h. sapporoensis, and tested the anti-inflammatory activity of the extracts by using a rat model of adjuvant-induced edema. The extracts derived from the queen of B. ignitus, the queen of B. terrestris, and the cocoon of B. ignitus decreased hind paw edema after 1 day of i.p. administration. These extracts also induced vasorelaxation and NO production in calf pulmonary artery endothelial cells. These results suggest that bumblebee alcohol extracts has anti-inflammatory and vasorelaxant properties.
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Ahn, M.Y., Han, J.W., Yoon, H.J. et al. Anti-inflammatory Effect of Bumblebee Alcohol Extracts in CFA-lnduced Rat Edema. Toxicol Res. 28, 249–253 (2012). https://doi.org/10.5487/TR.2012.28.4.249
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DOI: https://doi.org/10.5487/TR.2012.28.4.249