Review Article
Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum
Authors:
- Sander Van den EedeEmail Sander Van den Eede
- Nick Van de Voorde
- Filip Vanhoenacker
- Bart Op de Beeck
Abstract
A splenic lesion often represents a diagnostic challenge due to relative scarcity and the broad differential diagnosis. Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is usually encountered only incidentally. Although benign, patients with SANT often receive splenectomy, due to its rarity, diagnostic uncertainty and sometimes intimidating imaging morphology and size. Imaging features on computed tomography, magnetic resonance and positron emission tomography have a high diagnostic value for SANT and help differentiate this entity from other splenic lesions. When the imaging parameters are matched with core needle biopsy tissue analysis, further watchful waiting can be recommended in order to avoid splenectomy.
- Year: 2022
- Volume: 106 Issue: 1
- Page/Article: 12
- DOI: 10.5334/jbsr.2689
- Submitted on 21 Oct 2021
- Accepted on 28 Feb 2022
- Published on 5 Apr 2022
- Peer Reviewed