Published May 24, 2021 | Version v1
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  • 1. Laboratorio de Interacciones Moleculares, Facultad de Ciencias, Universidad de la República; Departamento de Genómica, Instituto de Investigaciones Biológicas Clemente Estable
  • 2. Laboratorio de Interacciones Moleculares, Facultad de Ciencias, Universidad de la República; Departamento de Genética, Facultad de Medicina, Universidad de la República

Description

Figure. Small RNA sequencing reads mapped to vtRNAs and its correlation to promoter DNA methylation of NCI-60 human tumor cell lines.

A. Mapping to vtRNAs sequence of small RNA reads of the NCI-60 cell line RXF393L. B. Normalized expression of vtRNAs (small RNA reads mapped to vtRNA gene) expressed as log2(CPM+1) of small RNA seq data for 59 NCI-60 human tumor cell lines, publicly available (SRA: PRJNA390643). Small RNA seq analysis as Fort et al. 2020. C. Pairwise Spearman correlations of vtRNA promoter DNA methylation average beta-values data (GEO: GSE49143) and normalized expression of vtRNAs log2(CPM+1).

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