Published February 4, 2021 | Version v2
Dataset Open

Pan-Cancer chromatin analysis of the human vtRNA genes - Supplementary Tables

  • 1. Laboratorio de Interacciones Moleculares, Facultad de Ciencias, Universidad de la República; Departamento de Genómica, Instituto de Investigaciones Biológicas Clemente Estable
  • 2. Laboratorio de Interacciones Moleculares, Facultad de Ciencias, Universidad de la República; Departamento de Genética, Facultad de Medicina, Universidad de la República

Description

Tables S1-S5. ATAC-seq and DNA methylation data for vtRNA promoters in primary tumors and normal adjacent tissue samples. CSV spreadsheets: Table_S1_ATAC-seq_data_500bp: All ATAC-seq data of vtRNAs promoter (500bp) data for primary tumor samples; Table_S2_DNA_methylation_500bp: All DNA methylation data and ATAC-seq data of vtRNAs promoter (500bp) data for total primary tumor and normal adjacent samples; Table_S3_DNA_methylation_NORMAL: All DNA methylation data of vtRNAs promoter (500bp) data for normal adjacent samples; Table_S4_DNA_methylation_TUMOR: All DNA methylation data of vtRNAs promoter (500bp) data for primary tumor samples; Table_S5_Normal_&_Tumor_matched: All DNA methylation data of vtRNAs promoter (500bp) data for primary tumor and normal adjacent samples.

Table S6. VtRNAs Transcription Factors Binding and KEEG enriched terms. CSV spreadsheets: Table_S6_Binding_Factors: Transcription factors identified in the cell line K562 as ChIP-seq Peaks by ENCODE 3 project and KEEG_terms: enriched KEGG pathway terms (FDR < 0.05).

Tables S7-S8. DNA methylation, ATAC-seq data and associated survival data for primary tumors. CSV spreadsheets: Table_S7_DNA-methylation_Survival_data: All DNA methylation data of vtRNAs promoter (500bp) and survival data for primary tumor samples; Table_S8_ATAC-seq_Survival_data: ATAC-seq data of vtRNAs promoter (500bp) and survival data for primary tumor samples.

Tables S9-S10. Correlation of ATAC-seq values between vtRNA and all genome promoters in primary tumor samples. CSV spreadsheets: Table_S9_ATAC-seq_gene_promoter_spearman_correlation: Spearman correlation values of all promoter genes and vtRNAs in primary tumors samples; Table_S10_vtRNAs_pathway_enrichment_and_cluster_chromosome_localization_analysis: vtRNAs vtRNA1-1, vtRNA1-2, vtRNA1-3 and vtRNA2-1 pathway enrichment and cluster chromosome localization data.

Tables S11-S14. ATAC-seq and DNA methylation data for vtRNA promoters in primary tumors and the associated Immune Subtypes data. CSV spreadsheets: Table_S11_Immune_Subtypes_DNA_methylation_data: All DNA methylation data of vtRNAs promoter (500bp) and Immune Subtypes data for primary tumor samples; Table_S12_Spearman_corr_vtRNAs_Immune_Subtypes_DNA_methylation_data: Spearman correlation values of DNA methylation data of vtRNAs promoter (500bp) and Immune Subtypes data for primary tumor samples; Table_S13_Immune_Subtypes_ATAC-seq_data: All ATAC-seq data of vtRNAs promoter (500bp) and Immune Subtypes data for primary tumor samples; Table_S14_Spearman_corr_vtRNAs_Immune_Subtypes_ATAC-seq_data: Spearman correlation values of ATAC-seq data of vtRNAs promoter (500bp) and Immune Subtypes data for primary tumor samples.

Notes

Pan-Cancer chromatin analysis of the human vtRNA genes uncovers their association with cancer biology. doi: https://doi.org/10.1101/2020.10.05.324723

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Table_S10_vtRNAs_pathway_enrichment_and_cluster_chromosome_localization_analysis.csv

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Is cited by
Preprint: 10.1101/2020.10.05.324723 (DOI)