Open Access, Peer-reviewed
pISSN 2234-8646
eISSN 2234-8840
    Korean J Pediatr Gastroenterol Nutr. 2011 Jun;14(2):181-186. Korean.
    Published online Jun 30, 2011.
    https://doi.org/10.5223/kjpgn.2011.14.2.181
    Copyright © 2011 The Korean Society of Pediatric Gastroenterology, Hepatology and Nutrition
    Case Report

    A Case of Non-IgE-mediated Eosinophilic Gastroenteritis Presenting as Ascites

    Eun Sang Yi, M.D., Mi Jin Kim, M.D., Sang Yun Ha, M.D.,* Yoo Min Lee, M.D., Kyong Eun Choi, M.D. and Yon Ho Choe, M.D.
      • Department of Pediatrics, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea.
      • *Department of Pathology, Samsung Medical Center, School of Medicine, Sungkyunkwan University, Seoul, Korea.
    • Corresponding author (Email: yonho.choe@samsung.com )
    Received April 18, 2011; Revised June 05, 2011; Accepted June 08, 2011.

    Abstract

    Eosinophilic gastroenteritis is a rare disease occurring especially in children, and shows various non-specific presentations with infiltration of eosinophils in the gastrointestinal organs. The pathophysiology of eosinophilic gastroenteritis is not yet clearly known, but allergic reactions are suspected to be related with the disease. Eosinophilic gastroenteritis is categorized into the mucosal, muscularis and subserosal types based on which layer of the intestinal wall is involved. There are different clinical manifestations according to the involved layer. Most cases to date have responded well to steroid therapy. In this study, we diagnosed and treated a case of non-IgE-mediated, subserosal eosinophilic gastroenteritis in a child with abdominal pain, diarrhea and ascites.

    Keywords
    Non-IgE-mediated; Eosinophilic gastroenteritis; Ascites

    Figures

    Fig. 1
    The ascitic fluid shows many eosinophils.

    Fig. 2
    Abdomen CT showed diffuse wall thickening of the small and large bowel.

    Fig. 3
    The endoscopic biopsy findings showed a marked eosinophil infiltration in the second portion of the duodenum (A) and the rectum (B) (H&E stain, 400).

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    MeSH Terms
    Abdominal Pain
    Ascites
    Child
    Diarrhea
    Enteritis
    Eosinophilia
    Eosinophils
    Gastritis
    Gastroenteritis
    Humans
    Hypersensitivity
    Rare Diseases
    Metrics
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