The Diagnostic Value of Prostate-specific Antigen and the Necessity of Routine Laboratory Examination for Early Detection

Sang Eun Lee

doi:10.5124/jkma.2004.47.5.403

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Lee: The Diagnostic Value of Prostate-specific Antigen and the Necessity of Routine Laboratory Examination for Early Detection

Special Issue

Prostate Cancer

Journal of the Korean Medical Association

Journal of the Korean Medical Association 2004; 47(5): 403-407.

Published online: 31 May 2004

DOI: https://doi.org/10.5124/jkma.2004.47.5.403

The Diagnostic Value of Prostate-specific Antigen and the Necessity of Routine Laboratory Examination for Early Detection

Sang Eun Lee, M.D.

Department of Urology, Seoul National University College of Medicine, Bundang Hospital, Korea. selee@snubh.org

Abstract

Current urologic literatures were evaluated to summarize current status of serum prostate specific antigen (PSA) in the early diagnosis of prostate cancer. Serum PSA is now a routine part of the investigation of men with suspected prostate cancer. While it still has its problems, in particular its lack of specificity, it is a very useful test. Since PSA may overlap in men with and without prostate cancer, other derivatives of PSA were developed to enhance the ability for detecting early stage prostate cancer. This review describes the current status and problems with PSA testing in prostate cancer diagnosis and highlights potential ways in which these may be reduced.

Keywords: Prostate-specific antigen, Prostate, Biopsy, Diagnosis

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References

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