有機合成化学協会誌
Online ISSN : 1883-6526
Print ISSN : 0037-9980
ISSN-L : 0037-9980
イミン類の不斉還元反応
橋口 昌平植松 信之野依 良治
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ジャーナル フリー

1997 年 55 巻 2 号 p. 99-109

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Of all options enantioselective reduction of imines is the most straightforward method for preparation of optically active amines. This asymmetric transformation can be accomplished by stoichiometric or catalytic hydroboration, aluminium hydride reduction, and, more efficiently, transition metal catalyzed reduction with organosilanes, molecular hydrogen, and formic acid. Various chiral catalysts containing Ti, Rh, Ir, and Ru have been developed for this purpose. This review summarizes the recent progress in this subject.

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