Ann Dermatol. 2000 Apr;12(2):130-133. English.
Published online Mar 16, 2016.
Copyright © The Korean Dermatological Association and The Korean Society for Investigative Dermatology
Original Article

A Case of Multiple Plexiform Schwannomas

Joo Hyun Shim, Tae Jong Chun, Myeung Nam Kim, Kye Yong Song and Byung In Ro

    Abstract

    Plexiform schwannoma is a relatively rare, benign peripheral nerve sheath tumor that can be located either in the deep soft tissues or in the dermis or subcutaneous tissue. This tumor may occur singly or as multiple lesions and may be localized to one anatomic site or diffusely distributed. Plexiform schwannoma should be differentiated with plexiform neurofibroma or other plexiform malignant tumors. We describe a case of a 6-year-old patient with multiple cutaneous plexiform schwannomas who had no other stigmata of neurofibromatosis 1 or family history suggesting a genetic disorder. The histopathological study revealed a tumor composed of multiple intradermal or subcutaneous interlacing and interconnecting fascicles and nodules that vary in size and shape. Characteristic Antoni A type cellular tissue showing frequent nuclear palisading and Verocay bodies were observed within well circumscribed elongated nodules.

    Keywords
    Multiple cutaneous plexiform schwannomas


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