Transitional cell tumours of the lacrimal drainage apparatus
Volume: 51 - Issue: 4
First page: 349 - Last page: 354
A.Z. Eweiss - V.J. Lund - A. Jay - G. Rose
BACKGROUND: Tumours of the lacrimal drainage apparatus (LDA) are very rare, but can be life-threatening. Seventy percent of lacrimal sac tumours are of epithelial origin, and transitional cell tumours represent an interesting sub-group of these epithelial tumours.
METHODS: A retrospective review of cases of LDA transitional cell tumours co-managed at the Royal National Throat Nose and Ear Hospital and Moorfields Eye Hospital, London.
RESULTS: Twenty cases of transitional cell tumours of the LDA were identified, comprising 10 transitional cell papillomas (TCPs) and 10 transitional cell carcinomas (TCCs). All cases were resected through a modified lateral rhinotomy approach. Limited resection of orbital fat with preservation of orbital functions was required for 2 cases of TCC. Fractionated external beam radiotherapy was administered in 7 cases of TCC. The mean follow up was 80 months (range 11 months-16 years). Recurrences were detected in 4 cases, which were managed by further surgery. Two cases have been lost to follow-up, but the 18 other patients are currently alive and disease free.
CONCLUSION: A favourable outcome can be achieved with transitional cell tumours of the LDA when an optimum management plan is followed.
Rhinology 51-4: 349-354, 2013
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