Published online Feb 28, 2009.
https://doi.org/10.4174/jkss.2009.76.2.127
Laparoscopic Treatment of Mesenteric Castleman's Disease
Abstract
Castleman's disease (CD) is an uncommon lymphoproliferative disorder of unknown origin. There are two histological types: hyaline-vascular type and plasma cell type. CD is usually located in the mediastinum, but may be seen in any site including the neck, axilla, mesentery, and retroperitoneum. A 52-year-old male complained of vague lower abdominal pain. There was no palpable mass and all laboratory data showed nonspecific findings. Abdominal computed tomography scan showed a solitary homogenous, well-defined mass in the mesentery. The laparoscopic complete resection was performed without complications. Histologic examination of resected lesion revealed the hyaline-vascular type of CD. In the hyaline-vascular type of CD, laparoscopic approach constitutes a complete treatment. We present here the case of laparoscopic treatment of isolated mesenteric CD.
Fig. 1
Abdominal computed tomography revealed the finding of homogeneous and well-enhancing mass (white arrow).
Fig. 2
Laparoscopy shows the tumor (black arrow) located in the mesenteric root.
Fig. 3
Gross finding of the resected specimen. The mass shows a 2.5×2 cm in size solid mass with homogenous cut surface.
Fig. 4
Microscopic finding of the specimen. (A) Some follicles with marked vascular proliferation and hyalinization. (H&E, ×40). (B) Germinal center with hyalinization and a tight concentric layering of lymphocytes. (onion-skin appearance) (H&E, ×200).
References
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Jeong CY, Lee YJ, Hong SC, Jung EJ, Choi SK, Joo YT, et al. Castleman's disease in unusual location; plasma cell variant. J Korean Surg Soc 2005;68:443–447.
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