Abstract
Gastritis cystica profunda (GCP) is a rare disease which shows multiple cystic gastric glands within the submucosa of the stomach. GCP lesions mainly develop at the site of gastroenterostomy and exhibit benign behavior. However, there have been a number of debates over its malignant potential. Several reports have documented GCP accompanied by gastric carcinomas, but the relationship between the two conditions remains uncertain. Here we report two cases of GCP with dysplasia accompanied by synchronous multiple early gastric cancers without previous gastric surgery.
REFERENCES
2. Littler ER, Gleibermann E. Gastritis cystica polyposa. (Gastric mucosal prolapse at gastroenterostomy site, with cystic and infiltrative epithelial hyperplasia). Cancer. 1972; 29:205–209.
3. Iwanaga T, Koyama H, Takahashi Y, Taniguchi H, Wada A. Diffuse submucosal cysts and carcinoma of the stomach. Cancer. 1975; 36:606–614.
4. Fonde EC, Rodning CB. Gastritis cystica profunda. Am J Gastroenterol. 1986; 81:459–464.
5. Bé chade D, Desramé J, Algayres JP. Gastritis cystic profunda in a patient with no history of gastric surgery. Endoscopy. 2007; 39(suppl 1):E80–E81.
7. Kim W, Park SC, Lee JY, et al. A case of gastric adenocarcinoma diagnosed after being followed up as submucosal tumor for 10 years. Korean J Gastointest Endosc. 2001; 37:291–295.
8. Yanagiwa H, Matsuzaki O, Ishihara A, Yoshimura H. Heterotopic gastric glands in the submucosa of the stomach. Acta Pathol Jpn. 1979; 29:347–350.
9. Park KH, Seong SG, Kim DK, et al. A case of Menetrier's disease association with gastritis profonda. Korean J Med. 1995; 48:811–815.
10. Okada M, Iizuka Y, Oh K, Murayama H, Maekawa T. Gastritis cystica profunda presenting as giant gastric mucosal fold: the role of endoscopic ultrasonography and mucosec-tomy in the diagnostic work-up. Gastrointest Endosc. 1994; 40:640–644.
11. Qizilbash AH. Gastritis cystica and carcinoma arising in old gastrojejunostomy stoma. Can Med Assoc J. 1975; 112:1432–1433.
12. Kurland J, DuBois S, Behling C, Savides T. Severe upper-GI bleeding caused by gastritis cystica profunda. Gastrointest Endosc. 2006; 63:716–717.
13. Koga S, Watanabe H, Enjoji M. Stomal polypoid hyper-trophic gastritis: a polypoid gastric lesion at gastroenterostomy site. Cancer. 1979; 43:647–657.
14. Mitomi H, Iwabuchi K, Amemiya A, Kaneda G, Adachi K, Asao T. Immuno- histochemical and analysis of a case of gastritis cystica profunda associated with carcinoma development. Scand J Gastroenterol. 1998; 33:1226–1229. .1.
15. Park JS, Myung SJ, Jung HY, et al. Endoscopic treatment of gastritis cystica polyposa found in an unoperated stomach. Gastrointest Endosc. 2001; 54:101–103. .1.
16. Cho HJ, Kim JE, Jeong BJ, et al. A case of gastric adenocarcinoma arising from gastritis cystica profunda. Korean J Gastrointest Endosc. 2004; 28:237–241.
17. Kim YS, Heo WS, Chae KH, et al. Our experience of gastritis cystica profunda cases and its clinical study. Korean J Gastrointest Endosc. 2006; 33:135–139.