MALT (Mucosa-Associated Lymphoid Tissue) Lymphoma of the Colon

Jong Hyeok Park; Jung Hwan Lee

doi:10.4166/kjg.2010.55.4.213

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Park and Lee: MALT (Mucosa-Associated Lymphoid Tissue) Lymphoma of the Colon

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Korean J Gastroenterol 2010;55(4):213-216.

Published online: 21 February 2010

DOI: https://doi.org/10.4166/kjg.2010.55.4.213

MALT (Mucosa-Associated Lymphoid Tissue) Lymphoma of the Colon

Jong Hyeok Park, M.D., Jung Hwan Lee, M.D.

Department of Internal Medicine, Seoul Paik Hospital, Inje Univercity College of Medicine, Seoul, Korea

Correspondence to: Jung Hwan Lee, M.D. Department of Internal Medicine, Seoul Paik Hospital, Inje University College of Medicine, 85, Jeo-dong 2-ga, Jung-gu, Seoul 100-032, Korea Tel: +82-2-2270-0012, Fax: +82-2-2270-0257 E-mail: jw0412@korea.com

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Fig. 1.

Colonoscopic findings. (A) A single sessile polypoid lesion was noted on the cecum. (B) The lesion was observed more clearly after spraying indigocarmine.

Fig. 2.

Histological findings. (A) Biopsy specimen showed diffuse infiltration of atypical lymphocytes in the mucosal layer (H&E, ×100). (B) Immunohistochemical stain for CD 20 was diffusely positive (×100), (C) and also stain for bcl-2 was positive (×100), (D) but stain for CD3 was negative (×100).

Fig. 3.

Miniprobe EUS showed an 1.2 cm sized hypoechoic mass with focally disrupted submucoal and intact proper muscle layer of colon.

Fig. 4.

Pathologic findings. (A) Gross specimen demonstrated multiple nodular lesions (arrows) on the cecum and terminal ileum. (B) The resection specimen showed diffuse infiltration of atypical lymphocytes in the mucosal and submucosal layer.

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