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    Korean J Urol. 2007 Mar;48(3):348-351. Korean.
    Published online Mar 31, 2007.
    https://doi.org/10.4111/kju.2007.48.3.348
    Copyright © 2007 The Korean Urological Association
    Case Report

    Male Patients with the Diagnoses of Synchronous Prostate and Breast Cancer

    Chang Yell Lee, Chang Soo Park, Wan Lee, Hee Suk Kwak,1 Mee Young Sol,2 and Moon Kee Chung
      • Department of Urology, Pusan National University College of Medicine, Busan, Korea.
      • 1Department of General Surgery, Pusan National University College of Medicine, Busan, Korea.
      • 2Department of Pathology, Pusan National University College of Medicine, Busan, Korea.
    • Corresponding author (Email: mkchung@ pusan.ac.kr )
    Received October 30, 2006; Accepted January 21, 2007.

    Abstract

    Prostate cancer and male breast cancer are similar in many ways, including the potential role of steroidal hormones in their pathogenesis and shared genetic abnormalities. However, the combination of these cancers in the same patient is rare. Herein, the case of a male patient, diagnosed with synchronous prostate and breast cancers, is reported.

    Keywords
    Synchronous neoplasms; Prostate cancer; Breast cancer

    Figures

    Fig. 1
    (A) The tumor cell nests forming a solid mass, with pushing margin infiltrates into normal breast parenchyma (H&E, ×100). (B) The tumor cells are large, with prominent nucleoli (H&E, ×400).

    Fig. 2
    Immunohistochemical staining for the prostate-specific antigen (PSA) (A) and prostate associated protein antigen (PAP) (B) showing negative reactions in a breast ductal carcinoma.

    Fig. 3
    (A) The small compact tumor cell nests infiltrating into the normal prostatic parenchyma (H&E, ×200). (B) The tumor cells have prominent basophilic nucleoli, which are characteristic of a prostatic adenocarcinoma (H&E, ×400).

    Fig. 4
    Immunohistochemical staining for the prostate-specific antigen (PSA) (A) and prostate associated protein antigen (PAP) (B) showing positive reactions.

    Tables

    Table 1
    Treatment of patients with male breast cancer and prostate cancer

    References

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    MeSH Terms
    Breast Neoplasms*
    Breast Neoplasms, Male
    Breast*
    Diagnosis*
    Humans
    Male*
    Neoplasms, Multiple Primary
    Prostate*
    Prostatic Neoplasms
    Metrics
    Share
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