Korean J Urol. 2006 Jun;47(6):667-669. Korean.
Published online Jun 30, 2006.
Copyright © 2006 The Korean Urological Association
Case Report

Localized Amyloidosis of the Prostate

Yong Seon Heo, Ki Hoon Kim, Jae Ho Han,1 Byung Cheol Ahn, Young Kyun Kim and Se Joong Kim
    • Department of Urology, Ajou University School of Medicine, Suwon, Korea.
    • 1Department of Pathology, Ajou University School of Medicine, Suwon, Korea.
Received February 07, 2006; Accepted March 31, 2006.

Abstract

The increasing number of prostatic biopsies, performed for the investigation of patients at risk of prostate cancer, will result in the more frequent identification of uncommon forms of prostatic pathology. Amyloidosis is a disease characterized by the extracellular deposition of insoluble amyloid fibrils, and may be either systemic or localized. Localized amyloidosis of the prostate is very rare. Herein, we report the case of a 34-year-old man with localized amyloidosis of the prostate, which was found via a transrectal ultrasound-guided prostatic biopsy due to an increased serum prostate-specific antigen level.

Keywords
Prostate; Amyloidosis; Biopsy; Prostate-specific antigen

Figures

Fig. 1
Microscopic finding of the specimen shows subepithelial deposition of amorphous, eosinophilic materials in the prostate (H&E, ×200).

Fig. 2
(A) Congo red-stained section of the prostate (×200). (B) Polarized light microscopy of section A disclosing an apple-green birefringence (×200).

References

    1. Sipe JD, Cohen AS. Amyloidosis. In: Kasper DL, Braunward E, Fauci AS, Hauser SL, Longo DL, Jameson JL, editors. Harrison's principles of internal medicine. 16th ed. New York: McGraw-Hill; 2005. pp. 2024-2029.
    1. Chung HS, Kwon SW, Kang DK, Park CM, Kim HK, Kang GH, et al. Primary localized amyloidosis of the ureter associated with osseous metaplasia. Korean J Urol 2004;45:189–193.
    1. McDonald JH, Heckel NJ. Primary amyloidosis of the lower genitourinary tract. J Urol 1956;75:122–132.
    1. Tripathi VN, Desautels RE. Primary amyloidosis of the urogenital system: a study of 16 cases and brief review. J Urol 1969;102:96–101.
    1. Babarczi E, Szijjarto F. Prostatic amyloidosis. Orv Hetil 1989;130:2749–2750.
    1. Mattocks S, Molyneux AJ, Doyle P. Localised amyloidosis of the prostate. Br J Urol 1993;72:655–656.
    1. Mark IR, Goodlad J, Lloyd-Davies RW. Localized amyloidosis of the genito-urinary tract. J R Soc Med 1995;88:320–324.
    1. Lupovitch A. The prostate and amyloidosis. J Urol 1972;108:301–302.
    1. Lawrentschuk N, Pan D, Stillwell R, Bolton DM. Implications of amyloidosis on prostatic biopsy. Int J Urol 2004;11:925–927.
    1. Wilson SK, Buchanan RD, Stone WJ, Rhamy RK. Amyloid deposition in the prostate. J Urol 1973;110:322–323.

Metrics
Share
Figures

1 / 2

PERMALINK