CC BY-NC-ND 4.0 · Indian J Plast Surg 2014; 47(01): 137-140
DOI: 10.4103/0970-0358.129650
Case Report
Association of Plastic Surgeons of India

Resolution of concomitant Achromobacter xylosoxidans burn wound infection without adjustment of antimicrobial therapy

Zhi Yang Ng
Burns Centre, Singapore General Hospital, Singapore
,
George Fang
Burns Centre, Singapore General Hospital, Singapore
,
Kah Woon Leo
Burns Centre, Singapore General Hospital, Singapore
› Author Affiliations
Further Information

Publication History

Publication Date:
26 August 2019 (online)

ABSTRACT

Achromobacter xylosoxidans is part of an emerging group of Gram negative bacterial infections with potentially severe sequelae, especially in the immunocompromised population such as burn patients. While antimicrobial therapy for patients with A. xylosoxidans bacteremia has been reported, the literature is scarce with regard to treatment in patients with positive tissue cultures only. Herein, we report our institution’s experience with such a case and a brief review of the current literature on this micro-organism in the setting of non-bacteremic infection.

 
  • REFERENCES

  • 1 Azzopardi EA, Azzopardi SM, Boyce DE, Dickson WA. Emerging gram-negative infections in burn wounds. J Burn Care Res 2011; 32: 570-6
  • 2 Fujioka M, Oka K, Kitamura R, Yakabe A, Chikaaki N. Alcaligenes xylosoxidans cholecystitis and meningitis acquired during bathing procedures in a burn unit: A case report. Ostomy Wound Manage 2008; 54: 48-53
  • 3 Puthucheary SD, Ngeow YF. Infections with Achromobacter xylosoxidans. Singapore Med J 1986; 27: 58-62
  • 4 Gómez-Cerezo J, Suárez I, Ríos JJ, Peña P, García de Miguel MJ, de José M. et al. Achromobacter xylosoxidans bacteremia: A 10-year analysis of 54 cases. Eur J Clin Microbiol Infect Dis 2003; 22: 360-3
  • 5 Vu-Thien H, Darbord JC, Moissenet D, Dulot C, Dufourcq JB, Marsol P. et al. Investigation of an outbreak of wound infections due to Alcaligenes xylosoxidans transmitted by chlorhexidine in a burns unit. Eur J Clin Microbiol Infect Dis 1998; 17: 724-6
  • 6 Eshwara VK, Mukhopadhyay C, Mohan S, Prakash R, Pai G. Two unique presentations of Achromobacter xylosoxidans infections in clinical settings. J Infect Dev Ctries 2011; 5: 138-41
  • 7 D’Amato RF, Salemi M, Mathews A, Cleri DJ, Reddy G. Achromobacter xylosoxidans (Alcaligenes xylosoxidans subsp. xylosoxidans) meningitis associated with a gunshot wound. J Clin Microbiol 1988; 26: 2425-6
  • 8 Aisenberg G, Rolston KV, Safdar A. Bacteremia caused by Achromobacter and Alcaligenes species in 46 patients with cancer (1989-2003). Cancer 2004; 101: 2134-40
  • 9 Jacquier H, Le Monnier A, Carbonnelle E, Corvec S, Illiaquer M, Bille E. et al Gmc Study Group In vitro antimicrobial activity of "last-resort" antibiotics against unusual nonfermenting Gram-negative bacilli clinical isolates. Microb Drug Resist 2012; 18: 396-401