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- HOME > Diabetes Metab J > Volume 30(5); 2006 > Article
- Case Report Clinical Courses of Two Women with Gestational Diabetes Mellitus Who are GAD Antibody Positive.
- Sung Hoon Yu, Min Jun Song, Sung Hoon Kim, Chang Hoon Yim, Ki Ok Han, Won Kun Park, Hyun Koo Yoon, Ho Yeon Chung
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Diabetes & Metabolism Journal 2006;30(5):398-402
DOI: https://doi.org/10.4093/jkda.2006.30.5.398
Published online: September 1, 2006
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1Department of Medicine, Cheil General Hospital, Sungkyunkwan University of School of Medicine, Korea.
2Department of Endocrinology and Metabolism, School of Medicine, Kyung Hee University, Korea.
2Department of Endocrinology and Metabolism, School of Medicine, Kyung Hee University, Korea.
Abstract
Gestational diabetes mellitus (GDM) is defined as glucose intolerance of various degrees with onset or first recognition during pregnancy. Women with GDM are at high risk of developing type 2 diabetes later in life, but the risk of developing type 1 diabetes is also increased. Positivity for glutamic acid decarboxylase (GAD) antibodies during pregnancy confers a high risk for subsequent progression to type 1 diabetes. Here, we reported the two cases with GDM who were GAD antibody positive and progressed to type 1 diabetes with different time-courses. One woman with GDM progressed rapidly to classical type 1 diabetes while the other became slowly progressive IDDM (SPIDDM) [or latent autoimmune diabetes in adults (LADA)].
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