Successful Treatment of Prosthetic Tricuspid Valve Thrombosis with Repeated Urokinase Therapy

Yang, Jeong Hoon; Kim, Sung Hea; Cho, Soo Jin; Kim, Jong Kyu; Lee, Sang-Chol; Park, Kay-Hyun; Park, Seung Woo

doi:10.4070/kcj.2006.36.5.400

Korean Circ J. 2006 May;36(5):400-403. English.
Published online May 31, 2006.
https://doi.org/10.4070/kcj.2006.36.5.400

Case Report

Successful Treatment of Prosthetic Tricuspid Valve Thrombosis with Repeated Urokinase Therapy

Jeong Hoon Yang, MD,¹ Sung Hea Kim, MD,¹ Soo Jin Cho, MD,¹ Jong Kyu Kim, MD,¹ Sang-Chol Lee, MD,¹ Kay-Hyun Park, MD,² and Seung Woo Park, MD¹

Author information

Author notes

Copyright and License

- ¹Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
- ²Department of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.
Email: swpark@smc.samsung.co.kr

Received September 26, 2005; Accepted October 26, 2005.

Abstract

Prosthetic valve thrombosis (PVT) can be a life-threatening complication that requires immediate treatment. This is a case report on repeated thrombolytic therapy for thrombosis of a prosthetic tricuspid valve. After repeated urokinase therapy, mechanical clicks were audible and the hemodynamics of the patient rapidly improved. Echocardiography showed the disappearance of thrombi and a normalized pressure gradient. Cine-fluoroscopy showed a well-functioning prosthetic valve.

Keywords

Thrombosis; Thrombolytic therapy