Korean Circ J. 1998 Jul;28(7):1131-1140. Korean.
Published online Jul 31, 1998.
Copyright © 1998 The Korean Society of Circulation
Original Article

A Review of Cardiac Myxoma: 33-year Experience in a Single Institution

Woong Chol Kang, M.D., Jong-Won Ha, M.D., Byung-Chul Chang, M.D., Jin-Wuk Kwon, M.D., Se-Joong Rim, M.D., Namsik Chung, M.D., Seung Yun Cho, M.D., Sung Soon Kim, M.D., Meyun Shick Kang, M.D., Sang-Ho Cho, M.D. and Bum Koo Cho, M.D.
    • Cardiology Division, Yonsei University, College of Medicine, Seoul, Korea.

Abstract

Background and Objectives

Cardiac myxomas are uncommon. Early diagnosis and treatment are essential to reduce morbidity or mortality. Before 1970, preoperative diagnosis was difficult. With the development of echocardiography, a correct diagnosis is made before operation. We reviewed our clinical experience in diagnosis and management of 52 cases of myxomas seen over a 33-year period, 1966 to 1998.

Patients and Methods

There were 20 males (38%) and 32 females (62%);age range 7 - 80. All the patient's medical records were reviewed. In twenty-five patients in whom echocardiographic features could be reviewed, clinical fetures were compared according to two distinct echocardiographic features;Round and polypoid type.

Results

Eighty-four percents of the presenting symptoms were cardiac origin while systemic embolism (SE) accounted for 15%. Echocardiography was used most often for diagnosis. The myxomas were located in the left atrium in 50 (96%), right atrium in 2 (4%). One patient had multiple myxoma. The incidence of SE was significantly higher in polypoid type than in round type (58% vs 0%, p<0.05). Multivariate regression analysis revealed polypoid type was the only independent predictor of SE (p=0.0029). Follow-up duration was ranged from 1 to 266 months. There was no deaths associated with myxoma. One patient presented with a recurrence 3 years after resection, and reoperation was performed uneventfully.

Conclusion

Due to the nonspecific presentation of myxoma, a high index of suspicion is needed. Surgical excision of myxoma can be considered curative with excellent long-term result. However, because of high possible occurrence of SE, a close attention should be given to those patients who have myxoma of polypoid type.

Keywords
Cardiac myxoma; Systemic embolism; Echocardiography; Surgical excision


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