A Clinical Trial on Antihypertensive Effect of Pindolol(Visken®)

Park, Jang Geun; Sohn, Gyo Ik; Bae, Sang Gun; Park, Byeung Yeub; Shin, Yeong Woo; Shin, Young Kee

doi:10.4070/kcj.1986.16.2.285

Korean Circ J. 1986 Jun;16(2):285-289. Korean.
Published online Jun 30, 1986.
https://doi.org/10.4070/kcj.1986.16.2.285

Original Article

A Clinical Trial on Antihypertensive Effect of Pindolol(Visken®)

Jang Geun Park, M.D., Gyo Ik Sohn, M.D., Sang Gun Bae, M.D., Byeung Yeub Park, M.D., Yeong Woo Shin, M.D. and Young Kee Shin, M.D.

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Copyright and License

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The antihypertensive effect and side reaction of pindolol were studied in 48 cases of essential hypertension 5mg to 15mg once regiment for average period of 6 weeks.

1) Average reduction of 25.11mmHg in systolic and 16.36mmHg in diastolic pressure were observed and their percentile reduction was 15.20% and 14.79%, respectively. The overall effect rate was 83.21%. The blood pressure was lowered significantly since 1 week of both in systolic and diastolic pressure with the daily of 10-15mg.

2) There was no significant change in heart rate before and after treatment.

3) No specific side reaction was observed except 1 cases in which discontinued the medication because of severe headache and fatigability on 2nd day of medication.