J Korean Orthop Assoc. 2016 Oct;51(5):395-402. Korean.
Published online Oct 26, 2016.
Copyright © 2016 by The Korean Orthopaedic Association
Original Article

Analysis of the Factors Affecting Bone Union after Open-Wedge High Tibial Osteotomy and Graft Material for Lateral Cortex Fractures

Jin-Hyeok Seo, M.D., Do-Hun Kim, M.D., Seung-Suk Seo, M.D., Yeon-Gu Kim, M.D., Ok-Gul Kim, M.D. and Beyoung-Yun Park, M.D.
    • Department of Orthopedic Surgery, Bumin Hospital, Busan, Korea.
Received March 07, 2016; Revised April 26, 2016; Accepted May 07, 2016.

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Purpose

The purpose of this study was to analyze patient factors including smoking, body mass index, correction angle, graft material, presence of lateral cortex fracture, and age for the effect on bone union after open-wedge high tibial osteotomy and the effect of graft material used for lateral cortex fractures.

Materials and Methods

This retrospective study was conducted on 54 patients and 58 cases with osteoarthritic change Kallgren-Lawrence grade 2 or less from May 2012 to June 2014. Average follow-up period was 22 months (14–38 months). The patients were divided into two groups according to patient related factors and graft materials (allograft, n=6; beta-tricalcium phosphate [β-TCP], n=6) used for lateral cortex fractures and were analyzed for the relationship with bone union after open-wedge high tibial osteotomy. Radiographic and clinic analyses were performed, and van Hemert grading was used for grading bone union at 6 weeks, 3 months, 6 months, and 1 year postoperatively.

Results

The non-smoking group and the group without lateral cortex fracture showed significantly higher bone union rates than the control group. No significant clinical or radiological difference was observed between the two groups in 12 cases and the allograft group showed significantly higher rates of union at 6 months and 1 year postoperatively according to the van Hemert grading.

Conclusion

Smoking and the presence of a lateral cortex fracture is a risk factor for nonunion in medial open-wedge high tibial osteotomy. The use of allograft material rather than β-TCP for lateral cortex fractures is thought to result in better bone union.

Keywords
knee; osteoarthritis; open wedge high tibial osteotomy; allografts; β-tricalcium phosphate

Tables

Table 1
Demographic Data of the Patients

Table 2
Grading of van Hemert10)

Table 3
Demographic Data and Surgical Factors in Patients with Bone Union Grade

Table 4
Demographic Data of Patients in the Allograft Group and β-TCP Group with Lateral Cortex Fracture

Table 5
Radiologic Assessment of the Allograft Group and β-TCP Group in Damaged Lateral Cortex

Table 6
Clinical Assessment of the Allograft Group and β-TCP Group in Damaged Lateral Cortex

Table 7
Bone Union Grade of the Allograft Group and β-TCP Group in Damaged Lateral Cortex

Notes

CONFLICTS OF INTEREST:The authors have nothing to disclose.

References

    1. Ministry for Health and Welfare. Elderly real state survey. Seoul: Ministry for Health and Welfare; 2009.
    1. Jackson JP, Waugh W. Tibial osteotomy for osteoarthritis of the knee. J Bone Joint Surg Br 1961;43-B:746–751.
    1. Coventry MB. Osteotomy about the knee for degenerative and rheumatoid arthritis. J Bone Joint Surg Am 1973;55:23–48.
    1. Benzakour T, Hefti A, Lemseffer M, El Ahmadi JD, Bouyarmane H, Benzakour A. High tibial osteotomy for medial osteoarthritis of the knee: 15 years follow-up. Int Orthop 2010;34:209–215.
    1. Keene JS, Dyreby JR Jr. High tibial osteotomy in the treatment of osteoarthritis of the knee. The role of preoperative arthroscopy. J Bone Joint Surg Am 1983;65:36–42.
    1. Staeheli JW, Cass JR, Morrey BF. Condylar total knee arthroplasty after failed proximal tibial osteotomy. J Bone Joint Surg Am 1987;69:28–31.
    1. Brouwer RW, Bierma-Zeinstra SM, van Raaij TM, Verhaar JA. Osteotomy for medial compartment arthritis of the knee using a closing wedge or an opening wedge controlled by a Puddu plate. A one-year randomised, controlled study. J Bone Joint Surg Br 2006;88:1454–1459.
    1. Spahn G. Complications in high tibial (medial opening wedge) osteotomy. Arch Orthop Trauma Surg 2004;124:649–653.
    1. van den Bekerom MP, Patt TW, Kleinhout MY, van der Vis HM, Albers GH. Early complications after high tibial osteotomy: a comparison of two techniques. J Knee Surg 2008;21:68–74.
    1. Agneskirchner JD, Freiling D, Hurschler C, Lobenhoffer P. Primary stability of four different implants for opening wedge high tibial osteotomy. Knee Surg Sports Traumatol Arthrosc 2006;14:291–300.
    1. Stoffel K, Stachowiak G, Kuster M. Open wedge high tibial osteotomy: biomechanical investigation of the modified Arthrex Osteotomy Plate (Puddu Plate) and the TomoFix Plate. Clin Biomech (Bristol, Avon) 2004;19:944–950.
    1. van Raaij TM, Brouwer RW, de Vlieger R, Reijman M, Verhaar JA. Opposite cortical fracture in high tibial osteotomy: lateral closing compared to the medial opening-wedge technique. Acta Orthop 2008;79:508–514.
    1. Brown CW, Orme TJ, Richardson HD. The rate of pseudarthrosis (surgical nonunion) in patients who are smokers and patients who are nonsmokers: a comparison study. Spine (Phila Pa 1976) 1986;11:942–943.
    1. Meidinger G, Imhoff AB, Paul J, Kirchhoff C, Sauerschnig M, Hinterwimmer S. May smokers and overweight patients be treated with a medial open-wedge HTO? Risk factors for non-union. Knee Surg Sports Traumatol Arthrosc 2011;19:333–339.
    1. Sloan A, Hussain I, Maqsood M, Eremin O, El-Sheemy M. The effects of smoking on fracture healing. Surgeon 2010;8:111–116.
    1. Lobenhoffer P, Agneskirchner J, Zoch W. Open valgus alignment osteotomy of the proximal tibia with fixation by medial plate fixator (in German). Orthopade 2004;33:153–160.
    1. Staubli AE, De Simoni C, Babst R, Lobenhoffer P. TomoFix: a new LCP-concept for open wedge osteotomy of the medial proximal tibia: early results in 92 cases. Injury 2003;34 Suppl 2:B55–B62.
    1. van Hemert WL, Willems K, Anderson PG, van Heerwaarden RJ, Wymenga AB. Tricalcium phosphate granules or rigid wedge preforms in open wedge high tibial osteotomy: a radiological study with a new evaluation system. Knee 2004;11:451–456.
    1. Jensen JA, Goodson WH, Hopf HW, Hunt TK. Cigarette smoking decreases tissue oxygen. Arch Surg 1991;126:1131–1134.
    1. Sarin CL, Austin JC, Nickel WO. Effects of smoking on digital blood-flow velocity. JAMA 1974;229:1327–1328.
    1. Jones JK, Triplett RG. The relationship of cigarette smoking to impaired intraoral wound healing: a review of evidence and implications for patient care. J Oral Maxillofac Surg 1992;50:237–239.
      discussion 239-40.
    1. Harvey EJ, Agel J, Selznick HS, Champman JR, Henley MB. Deleterious effect of smoking on healing of open tibia-shaft fractures. Am J Orthop (Belle Mead NJ) 2002;31:518–521.
    1. Miller BS, Dorsey WO, Bryant CR, Austin JC. The effect of lateral cortex disruption and repair in the stability of the medial opening wedge high tibial osteotomy. Am J Sports Med 2005;33:1552–1557.
    1. Yacobucci GN, Cocking MR. Union of medial opening-wedge high tibial osteotomy using a corticocancellous proximal tibial wedge allograft. Am J Sports Med 2008;36:713–719.
    1. Esenkaya I, Elmali N. Proximal tibia medial open-wedge osteotomy using plates with wedges: early results in 58 cases. Knee Surg Sports Traumatol Arthrosc 2006;14:955–961.
    1. Santic V, Tudor A, Sestan B, Legovic D, Sirola L, Rakovac I. Bone allograft provides bone healing in the medial opening high tibial osteotomy. Int Orthop 2010;34:225–229.
    1. Cho SW, Kim DH, Lee GC, Lee SH, Park SH. Comparison between autogenous bone graft and allogenous cancellous bone graft in medial open wedge high tibial osteotomy with 2-year follow-up. Knee Surg Relat Res 2013;25:117–125.
    1. Gouin F, Yaouanc F, Waast D, Melchior B, Delecrin J, Passuti N. Open wedge high tibial osteotomies: calcium-phosphate ceramic spacer versus autologous bonegraft. Orthop Traumatol Surg Res 2010;96:637–645.

Metrics
Share
Tables

1 / 7

PERMALINK