pISSN 1738-6756   eISSN 2092-9900
Open Access, Peer-reviewed
    J Breast Cancer. 2010 Dec;13(4):403-408. Korean.
    Published online Dec 31, 2010.
    https://doi.org/10.4048/jbc.2010.13.4.403
    Copyright © 2010 Korean Breast Cancer Society
    Original Article

    Efficacy of Breast Ultrasonography for Detection of Local, Regional, and Contralateral Recurrence of Breast Cancer

    Dong Sik Bae, Wonshik Han, Hyeong-Gon Moon, Woo Kyung Moon,1 Nariya Cho,1 Hansuk Kim, Soo Kyung Ahn, Seung Keun Oh, Yeo-Kyu Youn and Dong-Young Noh
      • Department of Surgery, Seoul National University College of Medicine, Seoul, Korea.
      • 1Department of Radiology, Seoul National University College of Medicine, Seoul, Korea.
    • Correspondence: Email: hanw@snu.ac.kr
    Received August 16, 2010; Accepted December 13, 2010.

    Abstract

    Purpose

    Breast ultrasonography (US) is not recommended for recurrence monitoring after breast cancer surgery due to the lack of evidence for its advantage. The purpose of this study was to evaluate the usefulness of US for detecting local recurrence (LR), regional recurrence (RR) and contralateral breast cancer (CBC) in breast cancer patients during follow-up.

    Methods

    The medical records of 5,833 breast cancer patients who underwent breast cancer surgery between January 2003 and December 2009 were reviewed retrospectively. Physical examination (PE), mammography (MMG), and US were done routinely to detect recurrences. Detection rate for locoregional and contralateral recurrence was compared between the three modalities.

    Results

    During the follow-up period, 125 LR, 46 RR, 83 CBC, and 29 synchronous local and regional recurrences developed in 245 patients among the study population of 5,833 breast cancer patients. Median time to recurrence was 34.7 months. The recurrence detection rate was 51.9%, 43.5%, and 90.1% for PE, MMG, and US, respectively. Mean size of the recurrent lesions detected by US (1.57 cm) was smaller than that of PE (2.69 cm) and MMG (2.03 cm) (p=0.002).

    Conclusion

    Breast US had higher recurrence detection rate for LR, RR, and CBC than PE or MMG after breast cancer surgery.

    Keywords
    Breast neoplasms; Local neoplasm recurrences; Mammography; Ultrasonography

    Figures

    Figure 1
    Incidence of 283 recurrence during the follow-up period.

    Tables

    Table 1
    Clinical characteristics of 245 patients who developed local, regional, or contralateral breast tumor recurrences

    Table 2
    Detection rate of each diagnostic method according to the type of recurrence

    Table 3
    Detection rate of each diagnostic method for ipsilateral breast tumor recurrence after breast conserving surgery

    Table 4
    Mean size of recurrent lesion according to the diagnostic modalities

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    MeSH Terms
    Breast
    Breast Neoplasms
    Follow-Up Studies
    Humans
    Imidazoles
    Mammography
    Medical Records
    Neoplasm Recurrence, Local
    Nitro Compounds
    Physical Examination
    Recurrence
    Retrospective Studies
    Ultrasonography, Mammary
    Metrics
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