pISSN 1738-6756   eISSN 2092-9900
Open Access, Peer-reviewed
    J Breast Cancer. 2008 Sep;11(3):151-155. Korean.
    Published online Sep 30, 2008.
    https://doi.org/10.4048/jbc.2008.11.3.151
    Copyright © 2008 Korean Breast Cancer Society
    Case Report

    Intracystic Papillary Carcinoma in the Male Breast: A Case Report

    Sang Seob Yun, Seung Hye Choi, Seong Keun Kim, Jong Kyung Park, Jong Min Baek, Dong Ho Lee, Young Jin Seo, Woo Chan Park, Byung Joo Song, Se Jung Oh, Seong Lee, Sang Seol Jung, Eun Joo Seo,1 and Ki Ouk Min1
      • Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul, Korea.
      • 1Department of Clinical Pathology, College of Medicine, The Catholic University of Korea, Seoul, Korea.
    Received December 03, 2007; Accepted August 12, 2008.

    Abstract

    Intracystic papillary carcinoma of the breast is a variant of ductal carcinoma in situ (DCIS) characterized by the presence of papillary carcinoma within a cystically dilated duct. DCIS of the male breast is an uncommon disease, accounting for approximately 7% of all male breast carcinomas. Most DCIS in men is of the papillary type. We experienced one case of intracystic papillary carcinoma in the right breast of a 49-yr-old male and report the case with a review of the literature.

    Keywords
    Male breast tumor; Intracystic papillary carcinoma

    Figures

    Fig 1
    Ultrasonographic findings. This tumor is a 2.3×1.6 cm sized well marginated cystic mass with an internal fluid level (arrow) and an irregular solid component in the right subareolar area.

    Fig 2
    Fine needle aspiration cytology findings. There are two papillary structures consisting of a central core of stromal cells surrounded by layers of epithelial cells in a hemorrhagic background (H&E stain, ×100).

    Fig 3
    Gross specimen after excision. The tumor is a well-encapsulated round mass composed of friable solid tissue in a papillary pattern (arrow) and brown fluid.

    Fig 4
    Histopathologic findings (H&E stain A×100, B×200). Papillary proliferations of the tumor cells with a fibrovascular core within the cystically dilated duct are observed. The high power view shows the layering of tumor cells, loss of nuclear polarity, hyperchromasia and lack of myoepithelial cell layer.

    Fig 5
    Immunohistochemical stains of estrogen receptor is positive (A×200) and SMMHC is negative (B×200).

    Tables

    Table 1
    Intracystic papillary carcinoma in the male breast: clinical feature and treatment

    References

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    MeSH Terms
    Accounting
    Breast
    Breast Neoplasms, Male
    Carcinoma, Intraductal, Noninfiltrating
    Carcinoma, Papillary
    Humans
    Male
    Multiple Endocrine Neoplasia Type 1
    Metrics
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