J Korean Acad Nurs. 2013 Oct;43(5):658-668. Korean.
Published online Oct 31, 2013.
© 2013 Korean Society of Nursing Science
Original Article

Meta-analysis of Psychosocial Interventions to Reduce Pain in Patients with Cancer

Pok Ja Oh, and Suk Jung Han
    • Department of Nursing, Sahmyook University, Seoul, Korea.
Received April 02, 2013; Accepted August 29, 2013.

Abstract

Purpose

The purpose of this study was to investigate the effects of psychosocial interventions on pain in cancer patients.

Methods

Eight studies published between 1980 and 2012 in Korean and ten studies published between 2002 and 2012 in English met the inclusion criteria with a total of 1539 participants. Methodological quality assessed by Cochrane's Risk of Bias for randomized studies and Risk of Bias Assessment tool for non randomized studies. The data were analyzed by the RevMan 5.2 program of Cochrane library.

Results

Overall, study quality was moderate to high. Effect sizes were heterogeneous and subgroup analysis was done. Cognitive behavioral therapy (CBT) were effective for pain (ES= -0.35; 95% CI= -0.56, -0.13). Pain education studies measured with NRS and VAS were effective for pain (ES= -0.77; 95% CI= -1.01, -0.52). Publication bias was not detected.

Conclusion

This study support the use of psychosocial interventions administered to cancer patients for their pain management. However, more well-designed studies are needed.

Keywords
Neoplasm; Pain; Intervention studies; Meta-analysis

Figures

Figure 1
Flow of studies included from database search.

Figure 2
Forest plot of effect size and 95% CI by cognitive behavioral therapy on pain & funnel plot of effective sizes by standard error for pain.

Figure 3
Forest plot of effect size and 95% CI by education interventions on pain & funnel plot of effective sizes by standard error for pain.

Figure 4
Forest plot of effect size and 95% CI by psychosocial intervention on pain & funnel plot of effective sizes by standard error for pain.

Tables

Table 1
Characteristics of Included Studies (N=18)

Notes

This paper was supported by the Sahmyook University Research Fund in 2013(No: RI 2013029).

References

    1. Cohen J. In: Statistical power analysis for the behavioral science. 2nd ed. Hillsdale, NJ: Lawrence Erlbaum Associates; 1998.
    1. Devine EC. Meta-analysis of the effect of psychoeducational interventions on pain in adults with cancer. Oncol Nurs Forum 2003;30(1):75–89.
    1. Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315(7109):629–634.
    1. Fawzy FI, Fawzy NW, Arndt LA, Pasnau RO. Critical review of psychosocial interventions in cancer care. Arch Gen Psychiatry 1995;52(2):100–113.
    1. Galway K, Black A, Cantwell M, Cardwell CR, Mills M, Donnelly M. Psychosocial interventions to improve quality of life and emotional wellbeing for recently diagnosed cancer patients. Cochrane Database Syst Rev 2012;11:CD007064.
    1. Golden RN. Making advances where it matters: Improving outcomes in mood and anxiety disorders. CNS Spectr 2004;9 6 Suppl 4:14–22.
    1. Sheinfeld Gorin S, Krebs P, Badr H, Janke EA, Jim HS, Spring B, et al. Meta-analysis of psychosocial interventions to reduce pain in patients with cancer. J Clin Oncol 2012;30(5):539–547.
    1. Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ 2003;327(7414):557–560.
    1. Hodges LJ, Walker J, Kleiboer AM, Ramirez AJ, Richardson A, Velikova G, et al. What is a psychological intervention? A metareview and practical proposal. Psychooncology 2011;20(5):470–478.
    1. Jang SY, Park JS. The meta-analysis of the effect of acupressure for nausea and vomiting in cancer patients receiving chemotherapy. J Korean Oncol Nurs 2011;11(2):116–126.
    1. Jassim GA, Whitford DL, Grey IM. Psychological interventions for women with non-metastatic breast cancer (Protocol). Cochrane Database Syst Rev 2010;10:CD008729.
    1. Kim JN, I R. A review of research on the psychosocial interventions for the cancer patients. Korean J Health Psychol 2008;13(2):329–357.
    1. Kim MY, Oh PJ. Meta-analysis of the effectiveness on foot-reflexo- massage for cancer patients. J Korean Oncol Nurs 2011;11(2):127–135.
    1. Kim SY, Park JE, Seo HJ, Seo HS, Song HJ, Shin CM, et al. In: NECA's guidance for undertaking systematic reviews and meta-analyses for intervention. Seoul: National Evidence-based Healthcare Collaborating Agency; 2011.
    1. Kim YH, Kwon IK, Kim JH, Seol ME, Jun MH, Ham YH, et al. In: Cancer symptom management. Seoul: Hyunmoonsa; 2011.
    1. Korean Society Pharmacoepidemiology and Risk Management. Pharmacoepidemiology. Seoul: Seoul National University Press; 2011.
    1. Kwon IG. Paper presented at the Korean oncology nursing society continuing education: Spring 2004; Seoul: 2004 Jun 01.
    1. Min YC, Oh PJ. A meta-analysis of intervention studies on cancer pain. J Korean Oncol Nurs 2011;11(1):83–92.
    1. Montgomery GH, Bovbjerg DH. Presurgery distress and specific response expectancies predict postsurgery outcomes in surgery patients confronting breast cancer. Health Psychol 2004;23(4):381–387.
    1. National Cancer Information Center. Survival rate: Five-year cancer relative survival rates. 2013 [Retrieved January 30, 2013].
    1. Oh PJ, Choi HJ. The effect of patient education interventions on distress, self-care knowledge and self-care behavior of oncology patients: A meta-analysis. Asian Oncol Nurs 2012;12(4):257–266.
    1. Oh PJ, Kim YH. Meta-analysis of spiritual intervention studies on biological, psychological, and spiritual outcomes. J Korean Acad Nurs 2012;42(6):833–842.
    1. Oh SS. In: Meta-analysis: Theory and practice. Seoul: Konkuk University Press; 2009.
    1. Osborn RL, Demoncada AC, Feuerstein M. Psychosocial interventions for depression, anxiety, and quality of life in cancer survivors: Meta-analyses. Int J Psychiatry Med 2006;36(1):13–34.
    1. Raingruber B. The effectiveness of psychosocial interventions with cancer patients: An integrative review of the literature (2006-2011). ISRN Nurs 2011;2011:638218.
    1. Ranchor AV, Fleer J, Sanderman R, van der Ploeg KM, Coyne JC, Schroevers M. Psychological interventions for cancer survivors and cancer patients in the palliative phase (Protocol). Cochrane Database Syst Rev 2012;1:CD009511.
    1. Rehse B, Pukrop R. Effects of psychosocial interventions on quality of life in adult cancer patients: Meta analysis of 37 published controlled outcome studies. Patient Educ Couns 2003;50(2):179–186.
    1. Schwarzer G. Meta: Meta-analysis with R. Version 3.0-1. 2013 [Retrieved March 20, 2013].
    1. Sutton AJ, Duval SJ, Tweedie RL, Abrams KR, Jones DR. Empirical assessment of effect of publication bias on meta-analyses. BMJ 2000;320(7249):1574–1577.
    1. Tatrow K, Montgomery GH. Cognitive behavioral therapy techniques for distress and pain in breast cancer patients: A meta-analysis. J Behav Med 2006;29(1):17–27.

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