Brief Reports

Clozapine induced severe weight loss in resistant schizophrenia managed with risperidone add-on therapy

Authors:

Abstract

Clozapine is prescribed for resistant schizophrenia. It is usually associated with weight gain. There have been only a few reports of weight loss associated with clozapine treatment and we report two patients from Sri Lanka. The first patient lost 27% of bodyweight on clozapine while the second lost 17%. Both were clinically stable on clozapine, with marked reduction of psychotic symptoms. Adding risperidone helped to regain the lost weight in the described patients.

Keywords:

ClozapineWeightSchizophreniaSri Lanka
  • Year: 2020
  • Volume: 11 Issue: 2
  • Page/Article: 38-39
  • DOI: 10.4038/sljpsyc.v11i2.8259
  • Published on 2 Dec 2020
  • Peer Reviewed