Original Articles
Clinical spectrum of scrub typhus in Eastern India: A 3 year experience
Authors:
- Suprit Basu
- Sarbani Misra (Roy)
- Tanushree Mondal
- Maidul IslamEmail Maidul Islam
- Sumantra Sarkar
- Mrinal Kanti Das
- Malay Kumar Sinha
- Sumana Datta (Kanjilal)
- Supratim Datta
Abstract
Introduction: Scrub typhus is a serious public health problem in Eastern India.
Objectives: To study the clinical spectrum and complications of scrub typhus and its doxycycline responsiveness.
Method: This study was carried out over a 3 year period on 203 serologically confirmed scrub typhus cases in a tertiary care centre in Eastern India.
Results: Fever (100%), facial puffiness (66.5%), vomiting (51.7%) and headache (39.4%) were common symptoms whilst hepatosplenomegaly (61.6%) and generalised lymphadenopathy (60.1%) were common signs. Meningoencephalitis (33.4%) and shock (26.6%) were common complications. Shock, congestive heart failure (CHF), disseminated intravascular coagulation (DIC), haemophagocytic lymphohistiocytosis (HLH had delayed response to doxycycline therapy.
Conclusions: In this study meningoencephalitis and shock were the common complications of scrub typhus. Meningo-encephalitis, hepatitis and pneumonia had favourable doxycycline response whilst shock, CCF. DIC, HLH and AKI had delayed doxycycline response (p<0.05).
Sri Lanka Journal of Child Health, 2021; 50(4): 610-616
- Year: 2021
- Volume: 50 Issue: 4
- Page/Article: 610-616
- DOI: 10.4038/sljch.v50i4.9847
- Published on 5 Dec 2021
- Peer Reviewed