Diagnostic yield and outcome of transrectal ultrasound-guided prostate biopsy in Sri Lanka

Introduction: The study was aimed to determine the diagnostic yield and outcome of transrectal ultrasoundguided prostate biopsy (TRUSPB) in a cohort of Sri Lankan men.

Methods: A prospective study was conducted among 333 (median age: 70 years, range: 48-88) men from a single urology unit. All patients underwent TRUSPB for persistently elevated serum prostate specific antigen (PSA) ≥4.00 ng/mL or suspicious rectal examination.

Results: The prostate cancer (PCa) detection rate was 57.7%. The PCa detection rate for PSA levels of 4.00 to <10, 10.00 to <20, 20.00 to <40, 40.00 to <100 and ≥100.00 ng/mL were 15/43 (34.9%), 23/88 (26.1%), 41/72 (56.9%), 51/63 (81.0%) and 60/62 (96.8%) respectively. Ten patients required further biopsies for rising PSA despite a first benign biopsy and three had PCa. Mild complications were identified in 6.9% (n=23).