Electrospun Poly(ε-Caprolactone)/Bovine Hydroxyapatite (BHA) Composite Nanofibers for Bone Tissue Engineering

M. Kagan Keler; Sibel Daglilar; Oguzhan Gunduz

doi:10.4028/www.scientific.net/KEM.720.228

Paper Titles

Study of Morphological Behavior of Hydroxyapatite, EDTA Hydroxyapatite and Metal Doped EDTA Hydroxyapatite Synthesized by Chemical Co-Precipitation Method via Hydrothermal Route
p.210

Chemical State of Nitrogen in Nitrogen-Doped Hydroxyapatite Ceramics with Enhanced Bioactivity
p.215

Slip Casting Used as a Forming Technique for Hydroxyapatite Processing
p.219

Fabrication of Chitosan-Nano Hydroxyapatite Scaffold for Dental Tissue Engineering
p.223

Electrospun Poly(ε-Caprolactone)/Bovine Hydroxyapatite (BHA) Composite Nanofibers for Bone Tissue Engineering
p.228

Synthesis of Ag-Hydroxyapatite
p.234

Fabrication of Bioactive Glass Fiber Reinforced Polyamide with High Mechanical Performance by the Function of Apatite Nuclei
p.241

Fabrication of Bioactive Fiber Reinforced Polyetheretherketone by the Function of Apatite Nuclei
p.246

Synthesis and Characterization of CaO-SiO₂-MgO Bioactive Glass Produced by Sol-Gel
p.252

HomeKey Engineering MaterialsKey Engineering Materials Vol. 720Electrospun Poly(ε-Caprolactone)/Bovine...

Electrospun Poly(ε-Caprolactone)/Bovine Hydroxyapatite (BHA) Composite Nanofibers for Bone Tissue Engineering

Abstract:

Tissue engineering applications have opened a different future-promising era for critical injuries, defects and diseases. Bone tissue engineering is the part of tissue engineering which aims to stir up new practical bone re-formation via the interactive combination of biomaterials and cells. Poly (e-caprolactone) (PCL) is a unique semi crystalline polymer material which handles several important features such as biocompatibility, high biomedical durability and degradation properties. Bovine hydroxyapatite (BHA) is another biocompatible material which provides to get ultimate mechanical behavior in composite designs. Because of their high biocompatibility, PCL and BHA were integrated the electrospinning system together. The system was revised for multi-feeding needle equipment. Eight dissimilar tissue scaffolds were produced and investigated for this recent work.

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Periodical:

Key Engineering Materials (Volume 720)

Pages:

228-233

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.720.228

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Online since:

November 2016

Authors:

M. Kagan Keler*, Sibel Daglilar, Oguzhan Gunduz

Keywords:

Biopolymers, Electrospinning, Mechanical Testing, PCL

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References

[1] Ficai, D., Ficai, A., Dinu, E., Oprea, O., Sonmez, M., Kagan Keler, M., .. & Gunduz, O. (2015). Magnetic core shell structures: from 0D to 1D assembling. Current pharmaceutical design, 21(37), 5301-5311.

DOI: 10.2174/1381612821666150917093812

Google Scholar

[2] M.G. McKee, J.M. Layman, M.P. Cashion, T.E. Long, Phospholipid nonwoven electrospun membranes. Science, 311 (2006) 353-355.

DOI: 10.1126/science.1119790

Google Scholar

[3] X. Lu, C. Wang, Y. Wei, One-Dimensional Composite Nanomaterials: Synthesis by Electrospinning and Their Applications. Small 5 (2009) 2349-70.

DOI: 10.1002/smll.200900445

Google Scholar

[4] Agarwal, S., Greiner, A., & Wendorff, J. H. (2013). Functional materials by electrospinning of polymers. Progress in Polymer Science, 38(6), 963-991.

DOI: 10.1016/j.progpolymsci.2013.02.001

Google Scholar

[5] Gunduz, O., Erkan, E. M., Daglilar, S., Salman, S., Agathopoulos, S., & Oktar, F. N. (2008). Composites of bovine hydroxyapatite (BHA) and ZnO. Journal of Materials Science, 43(8), 2536-2540.

DOI: 10.1007/s10853-008-2497-1

Google Scholar

[6] D.G. Yu, C. Branford-White, G.R. Williams, S.W.A. Bligh, K. White, L.M. Zhu, N.P. Chatterton, Self- assembled liposomes from amphiphilic electrospun nanofibers. Soft Matter 7 (2011) 8239-47.

DOI: 10.1039/c1sm05961k

Google Scholar

[7] F. Croiser, A. -S. Duwez, C. Jérôme, A.F. Léonard, K. O. van der Werf, P. J. Dijkstra, M.L. Bennink, Mechanial Testing of Electropun PCL Fibers. Acta Biomaterialia 8 (2011) 218-224.

DOI: 10.1016/j.actbio.2011.08.015

Google Scholar

[8] Keler, M. K., Daglilar, S., Gunduz, O., Yuksek, M., Sahin, Y. M., Ekren, N.,. & Salman, S. (2016). Mechanical Behavior of PCL Nano Fibers. Key Engineering Materials, 696.

DOI: 10.4028/www.scientific.net/kem.696.196

Google Scholar

[9] Elzein, T., Nasser-Eddine, M., Delaite, C., Bistac, S., & Dumas, P. (2004). FTIR study of polycaprolactone chain organization at interfaces. Journal of colloid and interface science, 273(2), 381-387.

DOI: 10.1016/j.jcis.2004.02.001

Google Scholar

[10] Berzina-Cimdina, L., & Borodajenko, N. (2012). Research of calcium phosphates using Fourier transform infrared spectroscopy. INTECH Open Access Publisher.

DOI: 10.5772/36942

Google Scholar