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HomeKey Engineering MaterialsKey Engineering Materials Vol. 638Gelatin-PVP Hydrogels with Potential Skin Grafts...

Gelatin-PVP Hydrogels with Potential Skin Grafts Applications

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Abstract:

This work presents the synthesis and characterization of natural-synthetic hydrogels based on gelatin (Gel) and polyvinylpyrrolidone (PVP), with potential for skin grafts applications. The natural component, Gel insures the biocompatibility and biodegradability of the bicomponent system [1], while the synthetic counterpart, PVP, is a physiologic inert component, extensively used in medicine due to its water affinity and due to its capacity of confer elasticity to films and membranes with potential applications in skin grafts [2]. The obtained hydrogels were subjected to morpho-structural analysis and rheological and mechanical tests (traction). The water affinity of the systems was estimated and their capacity to generate porous substrates through freeze-drying was evaluated.

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BiomMedD 2014

Info:

Periodical:

Key Engineering Materials (Volume 638)

Pages:

38-46

DOI:

https://doi.org/10.4028/www.scientific.net/KEM.638.38

Citation:

Cite this paper

Online since:

March 2015

Authors:

Andrada Serafim, Daniela G. Petre, Lavinia Moraru, Horia Emil Cioflan, Eugeniu Vasile, Bogdan Mastalier-Manolescu, Marius Petrutescu, Izabela Cristina Stancu*

Keywords:

Gelatin, Polyvinylpyrrolidone, Semi-Interpenetrated Polymer Network, Skin Grafts

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* - Corresponding Author

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