Preparation and Characterization of Collagen by Hydrogel Formation Method

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Abstract:

A kind of medical collagen was prepared by hydrogel formation method. Chemical and physical properties were investigated by FTIR, amino acid analysis, SDS-PAGE, carbohydrate content analysis, heavy metal content analysis. Degradation experiments in vivo and subsequent histological investigations were carried out to evaluate the biological performance. The results suggested that the collagen achieved is promising in tissue engineering scaffold materials for a long-term (more than 12 weeks) implantation application.

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Periodical:

Key Engineering Materials (Volumes 288-289)

Pages:

377-380

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Online since:

June 2005

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[1] C.H. Lee: International Journal of Pharmaceutic. Vol. 221(2001), pp.1-22.

Google Scholar

[2] D.G. Wallace et al: Advanced Drug Delivery Reviews. Vol. 55(2003), pp.1631-1649.

Google Scholar

[3] Koide. M: J. Biomed. Mater. Res. Vol. 27(1993), pp.79-87.

Google Scholar

[4] K.J. Payne et al: Biopolymer. Vol. 27(1988), pp.1747-1760.

Google Scholar

[5] M. JACKSON et al: Biochimical et Biophysica Acta. Vol. 1270(1995), pp.1-6.

Google Scholar

[6] J.M. Mcpherson et al: Collagen Related Research. Vol. 5(1985), pp.119-135.

Google Scholar

[7] R.A. Gelman et al: The Journal of Biological Chemistry. Vol. 254(1979).

Google Scholar